Institute of Sport Sciences, The Jerzy Kukuczka Academy of Physical Education, Katowice, Mikołowska 72A, 40-065, Katowice, Poland.
Faculty of Physical Culture, Palacký University Olomouc, třída Míru 117, 779 00, Olomouc, Czech Republic.
BMC Geriatr. 2021 Jan 6;21(1):11. doi: 10.1186/s12877-020-01952-7.
The associations between physical activity and metabolic syndrome (MetS) have been mainly found in cross-sectional studies. The aim of this longitudinal study was to examine the relationship between meeting step-based guidelines and changes in the risk of metabolic syndrome.
This study included data from older women (baseline age 62.9 ± 4.3 years) from a 7-year longitudinal study in Central Europe. At baseline and follow-up, physical activity was measured by an accelerometer, and the risk for MetS was assessed according to the NCEP-ATP III criteria. In 59 women, multivariate repeated measures ANOVA was used to compare differences in changes in the risk of MetS in groups based on meeting step-based guidelines (10,000 steps/day and 9000 steps/day for women aged <65 and ≥ 65 years, respectively).
Over 7 years, steps/day increased from 10,944 ± 3560 to 11,652 ± 4865, and the risk of MetS decreased from 41 to 12% in our sample. Women who longitudinally met step-based guidelines had a significantly higher mean concentration of high-density cholesterol (HDL-C) (64.5 and 80.3 mg/dL at baseline and follow-up, respectively) and a lower concentration of triglycerides (TGs) (158.3 and 123.8 mg/dL at baseline and follow-up, respectively) at follow-up compared to baseline. Moreover, women who increased their daily steps over 7 years to the recommended steps/day value significantly decreased the concentration of TGs (158.3 mg/dL and 123.8 mg/dL at baseline and follow-up, respectively).
Our study might suggest that the long-term meeting of step-based guidelines or an increase in daily steps/day to achieve the recommended value could be related to a lower risk of MetS, specifically in concentrations of HDL-C and TG. These findings may help in designing interventions aiming to decrease the risk of MetS in older women.
体力活动与代谢综合征（MetS）之间的关联主要在横断面研究中发现。本纵向研究的目的是检验符合基于步数的指南与代谢综合征风险变化之间的关系。
本研究纳入了来自中欧为期 7 年纵向研究的老年女性（基线年龄 62.9±4.3 岁）的数据。在基线和随访时，使用加速度计测量体力活动，根据 NCEP-ATP III 标准评估 MetS 风险。在 59 名女性中，采用多变量重复测量方差分析比较了根据是否符合基于步数的指南（<65 岁女性每天 10000 步和≥65 岁女性每天 9000 步）分组的女性在 MetS 风险变化方面的差异。
在 7 年内，每天的步数从 10944±3560 增加到 11652±4865，我们样本中的 MetS 风险从 41%降至 12%。与基线相比，长期符合基于步数的指南的女性在随访时高密度胆固醇（HDL-C）的平均浓度显著更高（分别为 64.5 和 80.3mg/dL），甘油三酯（TGs）的浓度更低（分别为 158.3 和 123.8mg/dL）。此外，与基线相比，7 年内每天步数增加到推荐值的女性 TG 浓度显著降低（分别为 158.3mg/dL 和 123.8mg/dL）。
我们的研究结果可能表明，长期符合基于步数的指南或增加每天的步数以达到推荐值可能与降低 MetS 风险有关，尤其是与 HDL-C 和 TG 浓度有关。这些发现可能有助于设计旨在降低老年女性 MetS 风险的干预措施。
