Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Rockville, MD, 20895, USA.
Br J Cancer. 2021 Apr;124(9):1467-1468. doi: 10.1038/s41416-020-01231-7. Epub 2021 Jan 22.
Despite experimental and mechanistic data suggesting circadian disruption's role in carcinogenesis, mixed findings from epidemiological investigations of artificial light at night and cancer risk in the general population are difficult to interpret due to exposure assessment limitations. It will be important for future studies to assess and validate individual-level exposures, ideally over the lifetime.
尽管有实验和机制数据表明昼夜节律紊乱在致癌作用中的作用,但由于暴露评估的局限性,人群中夜间人工光照与癌症风险的流行病学研究的混合结果很难解释。未来的研究对于评估和验证个体水平的暴露非常重要,理想情况下是在整个生命周期内进行。