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用于疫情防控的智能检测与选择性隔离。

Smart testing and selective quarantine for the control of epidemics.

作者信息

Pezzutto Matthias, Bono Rosselló Nicolás, Schenato Luca, Garone Emanuele

机构信息

Dipartimento di Ingegneria dell'Informazione, University of Padova, via Gradenigo 6b Padova, Italy.

Service d'Automatique et d'Analyse des Systèmes: Université Libre de Bruxelles (ULB), Av. F.D. Roosvelt 50, CP 165/55, 1050 Brussels, Belgium.

出版信息

Annu Rev Control. 2021;51:540-550. doi: 10.1016/j.arcontrol.2021.03.001. Epub 2021 Mar 26.

Abstract

This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related to the problem of optimal sensor selection, which is a very active research subject in control engineering. The goal of this paper is to propose a policy to smartly select the individuals to be tested. The main idea is to model the epidemics as a stochastic dynamic system and to select the individual to be tested accordingly to some optimality criteria, e.g. to minimize the probability of undetected asymptomatic cases. Every day, the probability of infection of the different individuals is updated making use of the stochastic model of the phenomenon and of the information collected in the previous days. Simulations for a closed community of 10'000 individuals show that the proposed technique, coupled with a selective confinement policy, can reduce the spread of the disease while limiting the number of individuals confined if compared to the simple contact tracing of positive and to an off-line test selection strategy based on the number of contacts.

摘要

本文基于这样的观察

在新冠疫情期间,选择对哪些个体进行检测对选择性隔离措施的有效性有重要影响。这个决策问题与最优传感器选择问题密切相关,而最优传感器选择问题是控制工程中一个非常活跃的研究课题。本文的目标是提出一项政策,以明智地选择待检测的个体。主要思路是将疫情建模为一个随机动态系统,并根据一些最优性标准(例如,最小化未检测到的无症状病例的概率)来选择待检测的个体。每天,利用该现象的随机模型和前几天收集的信息来更新不同个体的感染概率。对一个有10000人的封闭社区进行的模拟表明,与简单的阳性接触者追踪以及基于接触次数的离线检测选择策略相比,所提出的技术与选择性隔离政策相结合,可以在限制被隔离个体数量的同时减少疾病传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a87/7997562/2dbdfc347e34/gr1_lrg.jpg

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