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1
Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice.NOX2 过表达增加了小鼠心房颤动的诱发性，但不稳定性。
Cardiovasc Res. 2021 Sep 28;117(11):2354-2364. doi: 10.1093/cvr/cvab019.
2
Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation.心房肌细胞 NLRP3/CaMKII 连接形成术后心房颤动的底物。
Circ Res. 2020 Sep 25;127(8):1036-1055. doi: 10.1161/CIRCRESAHA.120.316710. Epub 2020 Jul 30.
3
Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy: A Translational Perspective.心房颤动病理生理学和治疗的分子基础：转化视角。
Circ Res. 2020 Jun 19;127(1):51-72. doi: 10.1161/CIRCRESAHA.120.316363. Epub 2020 Jun 18.
4
Attenuation of Oxidative Injury With Targeted Expression of NADPH Oxidase 2 Short Hairpin RNA Prevents Onset and Maintenance of Electrical Remodeling in the Canine Atrium: A Novel Gene Therapy Approach to Atrial Fibrillation.靶向表达 NADPH 氧化酶 2 短发夹 RNA 减轻氧化损伤可预防犬心房电重构的发生和维持：一种治疗心房颤动的新型基因治疗方法。
Circulation. 2020 Sep 29;142(13):1261-1278. doi: 10.1161/CIRCULATIONAHA.119.044127. Epub 2020 Jul 20.
5
Oxidative stress creates a unique, CaMKII-mediated substrate for atrial fibrillation in heart failure.氧化应激为心力衰竭中的心房颤动创造了一种独特的、CaMKII 介导的底物。
JCI Insight. 2018 Nov 2;3(21):120728. doi: 10.1172/jci.insight.120728.
6
Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation.增强的心肌细胞 NLRP3 炎性小体信号促进心房颤动。
Circulation. 2018 Nov 13;138(20):2227-2242. doi: 10.1161/CIRCULATIONAHA.118.035202.
7
Perioperative Rosuvastatin in Cardiac Surgery.心脏手术中的围手术期瑞舒伐他汀。
N Engl J Med. 2016 May 5;374(18):1744-53. doi: 10.1056/NEJMoa1507750.
8
Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death.线粒体氧化应激、连接蛋白 43 重构与心律失常性猝死。
Circ Arrhythm Electrophysiol. 2013 Jun;6(3):623-31. doi: 10.1161/CIRCEP.112.976787. Epub 2013 Apr 4.
9
Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins.心房来源的活性氧物种随心房颤动的持续时间和底物而变化：他汀类药物抗心律失常作用的意义。
Circulation. 2011 Sep 6;124(10):1107-17. doi: 10.1161/CIRCULATIONAHA.111.029223. Epub 2011 Aug 15.
10
Oxidative stress markers are associated with persistent atrial fibrillation.氧化应激标志物与持续性心房颤动相关。
Clin Chem. 2007 Sep;53(9):1652-7. doi: 10.1373/clinchem.2006.083923. Epub 2007 Jun 28.

Oxidative stress: a bystander or a causal contributor to atrial remodelling and fibrillation?

作者信息

Dobrev Dobromir, Dudley Samuel C

机构信息

Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.

Research Center, Montréal Heart Institute, University de Montréal, Montréal, QC 5000, Canada.

出版信息

Cardiovasc Res. 2021 Sep 28;117(11):2291-2293. doi: 10.1093/cvr/cvab124.

DOI:10.1093/cvr/cvab124
PMID:33822005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8479799/
Abstract
摘要