Division of Adolescent Medicine, Children's Mercy Kansas City, MO 64108, USA.
Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Kansas City, MO 64108, USA.
Pharmacogenomics. 2021 Apr;22(6):335-343. doi: 10.2217/pgs-2020-0177. Epub 2021 Apr 14.
Despite the expansion of pharmacogenetics (PGx), the views of pediatric patients remain unknown. This study explores adolescents' understanding and perceptions of PGx testing. Adolescents who had PGx testing were interviewed and their electronic health records were reviewed. Adolescents accurately described reason for testing and most felt the results impacted their current and future care. None perceived risks to securing future employment or insurance. All felt PGx would benefit their peers. Adolescents understand the reasons for PGx and perceive testing to be useful, low risk and applicable to peers. Findings from this study advocate for the inclusion of adolescents in shared decision-making regarding testing and for active engagement in the discussion of results.
尽管药物遗传学（PGx）不断发展，但儿科患者的观点仍不得而知。本研究旨在探讨青少年对 PGx 检测的理解和看法。对接受过 PGx 检测的青少年进行了访谈，并查阅了他们的电子健康记录。青少年准确地描述了检测的原因，大多数人认为检测结果影响了他们现在和未来的护理。没有人认为这会对未来的就业或保险产生风险。所有人都认为 PGx 将使他们的同龄人受益。青少年了解 PGx 的原因，并认为检测有用、风险低且适用于同龄人。本研究的结果提倡让青少年参与有关检测的共同决策，并积极参与结果讨论。
