Celedón Rodrigo Salazar, Díaz Leticia Barrientos
Laboratory of Molecular Applied Biology, Center of Excellence in Translational Medicine, Universidad de La Frontera, Temuco 4810296, Chile.
Scientific and Technological Bioresource Nucleus (BIOREN), Universidad de La Frontera, Temuco 4811230, Chile.
Microorganisms. 2021 Apr 1;9(4):739. doi: 10.3390/microorganisms9040739.
Microorganisms are considered one of the most promising niches for prospecting, production, and application of bioactive compounds of biotechnological interest. Among them, bacteria offer certain distinctive advantages due to their short life cycle, their low sensitivity to seasonal and climatic changes, their easy scaling as well as their ability to produce pigments of various colors and shades. Natural pigments have attracted the attention of industry due to an increasing interest in the generation of new products harmless to humans and nature. This is because pigments of artificial origin used in industry can have various deleterious effects. On this basis, bacterial pigments promise to be an attractive niche of new biotechnological applications, from functional food production to the generation of new drugs and biomedical therapies. This review endeavors to establish the beneficial properties of several relevant pigments of bacterial origin and their relation to applications in the biomedical area.
微生物被认为是寻找、生产和应用具有生物技术意义的生物活性化合物最具前景的领域之一。其中，细菌具有某些独特优势，因其生命周期短、对季节和气候变化敏感度低、易于扩大规模，以及能够产生各种颜色和色调的色素。由于对生产对人类和自然无害的新产品的兴趣与日俱增，天然色素已引起了工业界的关注。这是因为工业中使用的人工合成色素可能会产生各种有害影响。在此基础上，细菌色素有望成为从功能性食品生产到新药研发和生物医学治疗等新生物技术应用的一个有吸引力的领域。本综述致力于阐述几种相关细菌源色素的有益特性及其与生物医学领域应用的关系。
