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具有挑战性的美容创新:皮肤微生物群和益生菌保护皮肤免受紫外线诱导的损伤。

Challenging Cosmetic Innovation: The Skin Microbiota and Probiotics Protect the Skin from UV-Induced Damage.

作者信息

Souak Djouhar, Barreau Magalie, Courtois Aurélie, André Valérie, Duclairoir Poc Cécile, Feuilloley Marc G J, Gault Manon

机构信息

BASF Beauty Care Solutions France SAS, 69007 Lyon, France.

LMSM EA4312, Laboratoire de Microbiologie Signaux et Microenvironnement, Université de Rouen Normandie, 27000 Evreux, France.

出版信息

Microorganisms. 2021 Apr 27;9(5):936. doi: 10.3390/microorganisms9050936.

Abstract

Many studies performed in the last decade have focused on the cutaneous microbiota. It has been shown that this microbiota plays a key role in skin homeostasis. Considered as "a second barrier" to the environment, it is very important to know how it reacts to exogenous aggressions. The cosmetics industry has a started to use this microbiota as a source of natural ingredients, particularly ones that confer photoprotection against ultraviolet (UV) rays. Interestingly, it has been demonstrated that bacterial molecules can block UV rays or reverse their harmful effects. Oral probiotics containing living microorganisms have also shown promising results in restoring skin homeostasis and reversing the negative effects of UV rays. Microbial-based active sunscreen compounds have huge potential for use as next-generation photoprotection products.

摘要

在过去十年中进行的许多研究都聚焦于皮肤微生物群。研究表明,这种微生物群在皮肤内环境稳定中起着关键作用。它被视为抵御外界环境的“第二道屏障”,了解其对外源侵袭的反应非常重要。化妆品行业已开始将这种微生物群用作天然成分的来源,特别是那些具有抗紫外线光保护作用的成分。有趣的是,已证明细菌分子可以阻挡紫外线或逆转其有害影响。含有活微生物的口服益生菌在恢复皮肤内环境稳定和逆转紫外线的负面影响方面也显示出有前景的结果。基于微生物的活性防晒化合物作为下一代光保护产品具有巨大的应用潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b8/8145394/9ec300a2c5aa/microorganisms-09-00936-g001.jpg

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