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伯氏疏螺旋体所致淋巴细胞性脑脊神经根炎和脑脊髓炎:18例临床与血清学研究

Lymphocytic meningoradiculitis and encephalomyelitis due to Borrelia burgdorferi: a clinical and serological study of 18 cases.

作者信息

Sindic C J, Depre A, Bigaignon G, Goubau P F, Hella P, Laterre C

机构信息

Service de Neurologie, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

出版信息

J Neurol Neurosurg Psychiatry. 1987 Dec;50(12):1565-71. doi: 10.1136/jnnp.50.12.1565.

DOI:10.1136/jnnp.50.12.1565
PMID:3437290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1032595/
Abstract

Clinical features of 18 patients with either lymphocytic meningoradiculitis (n = 17) or chronic encephalomyelitis (n = 1) due to Borrelia burgdorferi are reported. Arthropod bites were recorded in only seven patients. High titres of anti B burgdorferi antibodies were detected in sera from all patients and in CSF from 12 out of 17 patients tested. All patients had CSF abnormalities especially pleocytosis and oligoclonal bands. A falsely positive syphilitic serology was observed in the CSF from the patient with encephalomyelitis.

摘要

报告了18例由伯氏疏螺旋体引起的淋巴细胞性脑脊神经根炎(17例)或慢性脑脊髓炎(1例)患者的临床特征。仅7例患者记录有节肢动物叮咬史。所有患者血清中均检测到高滴度抗伯氏疏螺旋体抗体,17例接受检测的患者中有12例脑脊液中也检测到该抗体。所有患者脑脊液均有异常,尤其是细胞增多和寡克隆带。在脑脊髓炎患者的脑脊液中观察到梅毒血清学假阳性。

相似文献

1
Lymphocytic meningoradiculitis and encephalomyelitis due to Borrelia burgdorferi: a clinical and serological study of 18 cases.伯氏疏螺旋体所致淋巴细胞性脑脊神经根炎和脑脊髓炎:18例临床与血清学研究
J Neurol Neurosurg Psychiatry. 1987 Dec;50(12):1565-71. doi: 10.1136/jnnp.50.12.1565.
2
Intrathecal production of specific antibodies against Borrelia burgdorferi in patients with lymphocytic meningoradiculitis (Bannwarth's syndrome).淋巴细胞性脑膜炎神经根炎(班沃思综合征)患者鞘内产生抗伯氏疏螺旋体的特异性抗体。
J Infect Dis. 1986 Feb;153(2):304-14. doi: 10.1093/infdis/153.2.304.
3
Oligoclonal Borrelia burgdorferi-specific IgG antibodies in cerebrospinal fluid in Lyme neuroborreliosis.莱姆病神经伯氏疏螺旋体病患者脑脊液中的寡克隆性伯氏疏螺旋体特异性IgG抗体
J Infect Dis. 1990 Jun;161(6):1194-202. doi: 10.1093/infdis/161.6.1194.
4
[Borrelia burgdorferi encephalomyelitis].
Rev Neurol (Paris). 1988;144(6-7):416-20.
5
[Meningoradiculitis caused by a spirochete (Borrelia burgdorferi) after arthropod bite].节肢动物叮咬后由螺旋体(伯氏疏螺旋体)引起的脑脊神经根炎
Rev Neurol (Paris). 1985;141(12):780-5.
6
Meningoradiculitis and encephalomyelitis due to Borrelia burgdorferi: a follow-up study of 72 patients over 27 years.伯氏疏螺旋体所致脑脊神经根炎和脑脊髓炎:27年间72例患者的随访研究
J Neurol. 1989 Sep;236(6):322-8. doi: 10.1007/BF00314373.
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[Serologic diagnosis of Borrelia burgdorferi infection].[伯氏疏螺旋体感染的血清学诊断]
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8
Bannwarth's syndrome: serum and CSF IgG antibodies against Borrelia burgdorferi examined by ELISA.班诺瓦特综合征:通过酶联免疫吸附测定法检测血清和脑脊液中抗伯氏疏螺旋体的IgG抗体。
Acta Neurol Scand. 1987 Jan;75(1):37-45. doi: 10.1111/j.1600-0404.1987.tb07886.x.
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Immunoglobulin abnormalities in cerebrospinal fluid and blood over the course of lymphocytic meningoradiculitis (Bannwarth's syndrome).淋巴细胞性脑膜炎神经根炎(班沃特氏综合征)病程中脑脊液和血液中的免疫球蛋白异常。
Ann Neurol. 1986 Sep;20(3):337-45. doi: 10.1002/ana.410200311.
10
[Lyme disease without arthritis: presence of antiBorrelia burgdorferi antibodies in meningoradiculitis following chronic erythema migrans].
Presse Med. 1985;14(28):1517-8.

引用本文的文献

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Poliomyelitis-like syndrome with matching magnetic resonance features in a case of Lyme neuroborreliosis.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0527. Epub 2009 Jan 23.
2
Poliomyelitis-like syndrome with matching magnetic resonance features in a case of Lyme neuroborreliosis.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.08.2008.0771. Epub 2009 Feb 2.
3
Poliomyelitis-like syndrome with matching magnetic resonance features in a case of Lyme neuroborreliosis.莱姆病神经螺旋体病患者出现具有匹配磁共振特征的脊髓灰质炎样综合征。
J Neurol Neurosurg Psychiatry. 2007 Oct;78(10):1160-1. doi: 10.1136/jnnp.2007.121103.
4
Meningoencephalomyeloradiculoneuritis in one case of Borrelia burgdorferi infection (Lyme disease).
Ital J Neurol Sci. 1989 Aug;10(4):457-61. doi: 10.1007/BF02334954.
5
Borrelia burgdorferi myelitis presenting as a partial stiff man syndrome.
J Neurol. 1990 Feb;237(1):51-4. doi: 10.1007/BF00319670.
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Intrathecal synthesis of anti-mycobacterial antibodies in patients with tuberculous meningitis. An immunoblotting study.结核性脑膜炎患者鞘内抗分枝杆菌抗体的合成。一项免疫印迹研究。
J Neurol Neurosurg Psychiatry. 1990 Aug;53(8):662-6. doi: 10.1136/jnnp.53.8.662.
7
Acute and chronic neuroborreliosis with and without CNS involvement: a clinical, MRI, and HLA study of 27 cases.
J Neurol. 1991 Aug;238(5):271-80. doi: 10.1007/BF00319739.

本文引用的文献

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Particle counting immunoassay (PACIA).颗粒计数免疫测定法(PACIA)。
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Lyme disease-a tick-borne spirochetosis?莱姆病——一种蜱传播的螺旋体病?
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Spirochetes isolated from the blood of two patients with Lyme disease.从两名莱姆病患者血液中分离出的螺旋体。
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The spirochetal etiology of Lyme disease.莱姆病的螺旋体病因
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The spirochetal etiology of lymphocytic meningoradiculitis of Bannwarth (Bannwarth's syndrome).班沃特淋巴细胞性脑膜神经根炎(班沃特综合征)的螺旋体病因。
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The antibody response in Lyme disease.莱姆病中的抗体反应。
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Isolation and cultivation of Lyme disease spirochetes.莱姆病螺旋体的分离与培养。
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Antibody response in Lyme disease: evaluation of diagnostic tests.莱姆病中的抗体反应:诊断测试评估
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Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin.莱姆病的神经系统异常:大剂量静脉注射青霉素治疗成功
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