Velu Rachel Milomba, Kwenda Geoffrey, Libonda Liyali, Chisenga Caroline Cleopatra, Flavien Bumbangi Nsoni, Chilyabanyama Obvious Nchimunya, Simunyandi Michelo, Bosomprah Samuel, Sande Nicholus Chintu, Changula Katendi, Muleya Walter, Mburu Monicah Mirai, Mubemba Benjamin, Chitanga Simbarashe, Tembo John, Bates Matthew, Kapata Nathan, Orba Yasuko, Kajihara Masahiro, Takada Ayato, Sawa Hirofumi, Chilengi Roma, Simulundu Edgar
Centre for Infectious Disease Research in Zambia, Lusaka P.O. Box 34681, Zambia.
Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka P.O. Box 32379, Zambia.
Pathogens. 2021 Aug 10;10(8):1007. doi: 10.3390/pathogens10081007.
Emerging and re-emerging mosquito-borne viral diseases are a threat to global health. This systematic review aimed to investigate the available evidence of mosquito-borne viral pathogens reported in Zambia. A search of literature was conducted in PubMed and Google Scholar for articles published from 1 January 1930 to 30 June 2020 using a combination of keywords. Eight mosquito-borne viruses belonging to three families, , and were reported. Three viruses (Chikungunya virus, Mayaro virus, Mwinilunga virus) were reported among the togaviruses whilst four (dengue virus, West Nile virus, yellow fever virus, Zika virus) were among the flavivirus and only one virus, Rift Valley fever virus, was reported in the family. The majority of these mosquito-borne viruses were reported in Western and North-Western provinces. and species were the main mosquito-borne viral vectors reported. Farming, fishing, movement of people and rain patterns were among factors associated with mosquito-borne viral infection in Zambia. Better diagnostic methods, such as the use of molecular tools, to detect the viruses in potential vectors, humans, and animals, including the recognition of arboviral risk zones and how the viruses circulate, are important for improved surveillance and design of effective prevention and control measures.
新出现和再次出现的蚊媒病毒病对全球健康构成威胁。本系统综述旨在调查赞比亚报告的蚊媒病毒病原体的现有证据。使用关键词组合在PubMed和谷歌学术上搜索了1930年1月1日至2020年6月30日发表的文章。报告了属于三个科（甲病毒科、黄病毒科、布尼亚病毒科）的八种蚊媒病毒。在甲病毒科中报告了三种病毒（基孔肯雅病毒、马亚罗病毒、姆维尼伦加病毒），在黄病毒科中有四种（登革病毒、西尼罗河病毒、黄热病毒、寨卡病毒），在布尼亚病毒科中仅报告了一种病毒，即裂谷热病毒。这些蚊媒病毒大多在西部和西北部省份被报告。埃及伊蚊和非洲伊蚊是报告的主要蚊媒病毒传播媒介。农业、渔业、人员流动和降雨模式是赞比亚与蚊媒病毒感染相关的因素。更好的诊断方法，如使用分子工具来检测潜在传播媒介、人类和动物中的病毒，包括识别虫媒病毒风险区以及病毒的传播方式，对于加强监测和设计有效的预防及控制措施很重要。
