Kapoor Nupur, Yadav Rahul
Department of Dentistry, Zydus Medical College and Hospital, Dahod, Gujarat, India.
Department of Surgery, Zydus Medical College and Hospital, Dahod, Gujarat, India.
Natl J Maxillofac Surg. 2021 May-Aug;12(2):233-237. doi: 10.4103/njms.NJMS_154_20. Epub 2021 Jul 15.
To assess the efficacy and feasibility of topical manuka honey application in chronic nonhealing discharging extraoral wounds.
The study includes 15 patients (9 males and 6 females, mean age: 38.06, range: 20-50 years), presenting with the complaint of chronic nonhealing discharging extraoral wounds from January 2018 to January 2020. After wound irrigation with normal saline, manuka honey in conjunction with the antibiotic treatment was directly applied onto the surface of the wound and was then covered by an absorbent layer to contain the honey. Dressings were changed every alternate day for a week till there was complete cessation of pus discharge. Henceforth, the interval between dressings was increased to 1 week subsequently and was continued for 4 weeks. Assessment was done on the basis of discharge and depth of the wound before the procedure and weekly for 4 weeks.
The average depth of wound as seen at 15 sites after a week was 5.72 mm, and decrease in the average depth of wound seen at the end of the 4 week was 0.88 mm with complete wound epithelization. This was found to be statistically significant ( = 0.0001). No cases were reported with allergy, pain, infection, inflammation, and swelling on 1, 2, 3, and 4week.
Hence, the use of manuka honey as a wound dressing material in our study has proved to promote the growth of tissues for wound repair, suppress inflammation, and bring about rapid autolytic debridement.
评估局部应用麦卢卡蜂蜜治疗慢性不愈合口腔外排脓伤口的疗效和可行性。
本研究纳入了15例患者（9例男性，6例女性，平均年龄：38.06岁，范围：20 - 50岁），这些患者在2018年1月至2020年1月期间因慢性不愈合口腔外排脓伤口前来就诊。用生理盐水冲洗伤口后，将麦卢卡蜂蜜与抗生素治疗联合直接应用于伤口表面，然后用吸收层覆盖以容纳蜂蜜。敷料每隔一天更换一次，持续一周，直至脓液完全停止排出。此后，敷料更换间隔增加至1周，并持续4周。在治疗前以及之后的4周内每周对伤口的排脓情况和深度进行评估。
一周后在15个部位观察到的伤口平均深度为5.72毫米，4周结束时伤口平均深度减少了0.88毫米，伤口完全上皮化。这在统计学上具有显著意义（P = 0.0001）。在第1、2、3和4周均未报告过敏、疼痛、感染、炎症和肿胀的病例。
因此，在我们的研究中，使用麦卢卡蜂蜜作为伤口敷料材料已证明可促进伤口修复组织的生长、抑制炎症并实现快速自溶性清创。
