用于检测胰腺癌标志物的石墨烯辅助电化学传感器。
Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers.
作者信息
Xu Zhenglei, Peng Minsi, Zhang Zhuliang, Zeng Haotian, Shi Ruiyue, Ma Xiaoxin, Wang Lisheng, Liao Bihong
机构信息
Department of Gastroenterology, The Second Clinical Medical College, Shenzhen People's Hospital, Jinan University, Shenzhen, China.
Department of Cardiology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China.
出版信息
Front Chem. 2021 Aug 19;9:733371. doi: 10.3389/fchem.2021.733371. eCollection 2021.
Abstract
Pancreatic cancer is a highly lethal gastrointestinal malignancy. Most patients are already in the middle to advanced stages of pancreatic cancer at the time of diagnosis and cannot be treated completely. As a single-atom planar two-dimensional crystal, graphene's unusual electronic structure, specific electronic properties and excellent electron transport capacity make it uniquely advantageous in the field of electrochemical sensing. In this mini-review, we summarize the potential application of graphene in pancreatic cancer detection. K-Ras gene, CEA and MicroRNA are important in the early diagnosis of pancreatic cancer.
摘要
胰腺癌是一种极具致死性的胃肠道恶性肿瘤。大多数患者在确诊时已处于胰腺癌的中晚期，无法得到根治。作为一种单原子平面二维晶体，石墨烯独特的电子结构、特定的电子性质和出色的电子传输能力使其在电化学传感领域具有独特优势。在本综述中，我们总结了石墨烯在胰腺癌检测中的潜在应用。K-Ras基因、癌胚抗原和微小RNA在胰腺癌的早期诊断中具有重要意义。
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