Sun Weiyi, Matsuoka Teruyuki, Narumoto Jin
Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Front Psychol. 2021 Nov 12;12:750803. doi: 10.3389/fpsyg.2021.750803. eCollection 2021.
The proportion of people with dementia has been increasing yearly, and the decision-making capacity of these people has become a major concern in fields such as the financial industry and in medical settings. In this narrative review, we discuss decision-making in people with Alzheimer's disease (AD), and we propose the support for decision-making in people with AD, especially financial and medical decision-making. We summarize several hypotheses and theories on the decision-making capacity of people with AD. These include the frontal lobe hypothesis, physiological theory, dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis, and the Person-Task-Fit (PTF) framework. Both internal and external factors can affect decision-making by people with AD. Internal factors are affected by changes in the brain and neurotransmitters, as well as alterations in cognitive ability and emotion. External factors include task characters, task contents, and situation influence. Since feedback has a significant effect on decision-making capacity, a series of suggestions may be helpful to improve this capacity, such as explicit advice, simple options, pleasant rewards, the Talking Mats approach, memory and organizational aid, support by caregivers, cognitive training and feedback. Thus, in providing decision-making support for people with AD, it is important to identify the internal and external factors that impair this process and to deal with these factors.
痴呆症患者的比例逐年上升,这些人的决策能力已成为金融行业和医疗环境等领域的主要关注点。在这篇叙述性综述中,我们讨论了阿尔茨海默病(AD)患者的决策问题,并提出了对AD患者决策的支持,特别是财务和医疗决策方面的支持。我们总结了关于AD患者决策能力的几种假设和理论。这些包括额叶假说、生理理论、下丘脑-垂体-肾上腺(HPA)轴功能障碍以及人-任务匹配(PTF)框架。内部和外部因素都会影响AD患者的决策。内部因素受大脑和神经递质变化以及认知能力和情绪改变的影响。外部因素包括任务特征、任务内容和情境影响。由于反馈对决策能力有显著影响,一系列建议可能有助于提高这种能力,例如明确的建议、简单的选择、愉快的奖励、谈话垫方法、记忆和组织辅助、照顾者的支持、认知训练和反馈。因此,在为AD患者提供决策支持时,识别损害这一过程的内部和外部因素并应对这些因素非常重要。