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中国河北省 2020 年 1 月至 2021 年 2 月期间的两波 COVID-19 疫情特征及应对措施。

The characteristics of and responses to the two COVID-19 outbreak waves in Hebei Province of China, January 2020 to February 2021.

机构信息

School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province510080, China.

One Health Center of Excellence for Research & Training, Sun Yat-Sen University, Guangzhou510080, China.

出版信息

Epidemiol Infect. 2021 Sep 17;149:e212. doi: 10.1017/S0950268821002089.

Abstract

Hebei Province was affected by two coronavirus disease 2019 (COVID-19) outbreak waves during the period 22 January 2020 through 27 February 2020 (wave 1) and 2 January 2021 through 14 February 2021 (wave 2). To evaluate and compare the epidemiological characteristics, containment delay, cluster events and social activity, as well as non-pharmaceutical interventions of the two COVID-19 outbreak waves, we examined real-time update information on all COVID-19-confirmed cases from a publicly available database. Wave 1 was closely linked with the COVID-19 pandemic in Wuhan, whereas wave 2 was triggered, to a certain extent, by the increasing social activities such as weddings, multi-household gatherings and church events during the slack agricultural period. In wave 2, the epidemic spread undetected in the rural areas, and people living in the rural areas had a higher incidence rate than those living in the urban areas (5.3 vs. 22.0 per 1 000 000). Furthermore, Rt was greater than 1 in the early stage of the two outbreak waves, and decreased substantially after massive non-pharmaceutical interventions were implemented. In China's 'new-normal' situation, development of targeted and effective intervention remains key for COVID-19 control in consideration of the potential threat of new coronavirus strains.

摘要

河北省在 2020 年 1 月 22 日至 2 月 27 日(第 1 波)和 2021 年 1 月 2 日至 2 月 14 日(第 2 波)期间受到了两波 2019 年冠状病毒病(COVID-19)疫情的影响。为了评估和比较两波 COVID-19 疫情的流行病学特征、遏制延迟、集群事件和社会活动以及非药物干预措施,我们从一个公开的数据库中检查了所有 COVID-19 确诊病例的实时更新信息。第 1 波与武汉的 COVID-19 大流行密切相关,而第 2 波在一定程度上是由农业淡季期间婚礼、多户聚会和教堂活动等社会活动增加引发的。在第 2 波疫情中,疫情在农村地区悄然蔓延,农村地区的发病率高于城市地区(每 100 万人 5.3 例 vs. 22.0 例)。此外,在两波疫情的早期,Rt 均大于 1,在实施大规模非药物干预措施后,Rt 大幅下降。在中国的“新常态”形势下,考虑到新的冠状病毒株可能带来的威胁,针对特定目标和有效干预措施的开发仍然是 COVID-19 控制的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e812/8485049/d9e8da57b73f/S0950268821002089_fig1.jpg

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