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了解加拿大 COVID-19 疫苗犹豫的全国趋势:2020 年 4 月至 2021 年 3 月期间进行的五次连续横断面代表性调查的结果。

Understanding national trends in COVID-19 vaccine hesitancy in Canada: results from five sequential cross-sectional representative surveys spanning April 2020-March 2021.

机构信息

Psychology, Université du Québec à Montréal, Montreal, Québec, Canada

Montreal Behavioural Medicine Centre, CIUSSS-NIM Research Centre, Montreal, Québec, Canada.

出版信息

BMJ Open. 2022 Apr 5;12(4):e059411. doi: 10.1136/bmjopen-2021-059411.

DOI:10.1136/bmjopen-2021-059411
PMID:35383087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8983402/
Abstract

OBJECTIVE

To examine rates of vaccine hesitancy and their correlates among Canadian adults between April 2020 and March 2021.

DESIGN

Five sequential cross-sectional age, sex and province-weighted population-based samples who completed online surveys.

SETTING

Canada.

PARTICIPANTS

A total of 15 019 Canadians aged 18 years and over were recruited through a recognised polling firm (Leger Opinion). Respondents were 51.5% female with a mean age of 48.1 (SD 17.2) years (range 18-95 years) and predominantly white (80.8%).

PRIMARY AND SECONDARY OUTCOME MEASURES

Rates of vaccine hesitancy over the five surveys (time points) and their sociodemographic, clinical and psychological correlates.

RESULTS

A total of 42.2% of respondents reported some degree of vaccine hesitancy, which was lowest during surveys 1 (April 2020) and 5 (March 2021) and highest during survey 3 (November 2020). Fully adjusted multivariate logistic regression analyses revealed that women, those aged 50 and younger, non-white, those with high school education or less, and those with annual household incomes below the poverty line in Canada were significantly more likely to report vaccine hesitancy, as were essential and healthcare workers, parents of children under the age of 18 and those who do not get regular influenza vaccines. Endorsing prevention behaviours as important for reducing virus transmission and high COVID-19 health concerns were associated with 77% and 54% reduction in vaccine hesitancy, respectively. Having high personal financial concerns was associated with 1.33 times increased odds of vaccine hesitancy.

CONCLUSIONS

Results highlight the importance of targeting vaccine efforts to specific groups by emphasising the outsized health benefits compared with risks of vaccination. Future research should monitor changes in vaccine intentions and behaviour to better understand underlying factors.

摘要

目的

调查 2020 年 4 月至 2021 年 3 月期间加拿大成年人疫苗犹豫率及其相关因素。

设计

五次连续的横断面年龄、性别和省份加权的基于人群的样本,他们完成了在线调查。

地点

加拿大。

参与者

共有 15019 名 18 岁及以上的加拿大人通过一家公认的民意调查公司(莱格民意调查)招募。受访者中 51.5%为女性,平均年龄为 48.1(17.2)岁(范围为 18-95 岁),主要为白人(80.8%)。

主要和次要结果

五次调查(时间点)的疫苗犹豫率及其社会人口统计学、临床和心理相关因素。

结果

共有 42.2%的受访者报告了某种程度的疫苗犹豫,这一比例在第一次调查(2020 年 4 月)和第五次调查(2021 年 3 月)期间最低,在第三次调查(2020 年 11 月)期间最高。完全调整的多变量逻辑回归分析显示,女性、50 岁及以下、非白人、高中及以下学历、加拿大收入低于贫困线的家庭、基本和医疗保健工作者、18 岁以下儿童的父母、以及不经常接种流感疫苗的人更有可能报告疫苗犹豫。认为预防行为对减少病毒传播很重要和对 COVID-19 健康问题高度关注与疫苗犹豫率分别降低 77%和 54%相关。个人财务问题严重与疫苗犹豫率增加 1.33 倍相关。

结论

结果强调了针对特定群体开展疫苗接种工作的重要性,强调了与接种风险相比,疫苗接种的巨大健康益处。未来的研究应监测疫苗接种意愿和行为的变化,以更好地了解潜在因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b7/8983402/da261f32139e/bmjopen-2021-059411f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b7/8983402/73f9c311b1c3/bmjopen-2021-059411f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b7/8983402/5c8598bad156/bmjopen-2021-059411f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b7/8983402/da261f32139e/bmjopen-2021-059411f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b7/8983402/73f9c311b1c3/bmjopen-2021-059411f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b7/8983402/5c8598bad156/bmjopen-2021-059411f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b7/8983402/da261f32139e/bmjopen-2021-059411f03.jpg

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