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基于深度学习的脑计算机断层扫描图像分类:通过迁移学习进行超参数优化以用于中风诊断

Deep Learning-Based Brain Computed Tomography Image Classification with Hyperparameter Optimization through Transfer Learning for Stroke.

作者信息

Chen Yung-Ting, Chen Yao-Liang, Chen Yi-Yun, Huang Yu-Ting, Wong Ho-Fai, Yan Jiun-Lin, Wang Jiun-Jie

机构信息

Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Keelung 204201, Taiwan.

Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Chang Gung University, Linkou 333423, Taiwan.

出版信息

Diagnostics (Basel). 2022 Mar 25;12(4):807. doi: 10.3390/diagnostics12040807.

Abstract

Brain computed tomography (CT) is commonly used for evaluating the cerebral condition, but immediately and accurately interpreting emergent brain CT images is tedious, even for skilled neuroradiologists. Deep learning networks are commonly employed for medical image analysis because they enable efficient computer-aided diagnosis. This study proposed the use of convolutional neural network (CNN)-based deep learning models for efficient classification of strokes based on unenhanced brain CT image findings into normal, hemorrhage, infarction, and other categories. The included CNN models were CNN-2, VGG-16, and ResNet-50, all of which were pretrained through transfer learning with various data sizes, mini-batch sizes, and optimizers. Their performance in classifying unenhanced brain CT images was tested thereafter. This performance was then compared with the outcomes in other studies on deep learning-based hemorrhagic or ischemic stroke diagnoses. The results revealed that among our CNN-2, VGG-16, and ResNet-50 analyzed by considering several hyperparameters and environments, the CNN-2 and ResNet-50 outperformed the VGG-16, with an accuracy of 0.9872; however, ResNet-50 required a longer time to present the outcome than did the other networks. Moreover, our models performed much better than those reported previously. In conclusion, after appropriate hyperparameter optimization, our deep learning-based models can be applied to clinical scenarios where neurologist or radiologist may need to verify whether their patients have a hemorrhage stroke, an infarction, and any other symptom.

摘要

脑部计算机断层扫描(CT)常用于评估脑部状况,但即使对于经验丰富的神经放射科医生来说,立即准确解读急诊脑部CT图像也很繁琐。深度学习网络常用于医学图像分析,因为它们能实现高效的计算机辅助诊断。本研究提出使用基于卷积神经网络(CNN)的深度学习模型,根据未增强的脑部CT图像结果,将中风有效分类为正常、出血、梗死及其他类别。纳入的CNN模型有CNN - 2、VGG - 16和ResNet - 50,所有这些模型都通过迁移学习,使用不同的数据大小、小批量大小和优化器进行了预训练。此后测试了它们在分类未增强脑部CT图像方面的性能。然后将该性能与其他基于深度学习的出血性或缺血性中风诊断研究的结果进行比较。结果显示,在我们通过考虑多个超参数和环境进行分析的CNN - 2、VGG - 16和ResNet - 50中,CNN - 2和ResNet - 50的表现优于VGG - 16,准确率达0.9872;然而,ResNet - 50得出结果所需的时间比其他网络更长。此外,我们的模型表现比之前报道的要好得多。总之,经过适当的超参数优化后,我们基于深度学习的模型可应用于临床场景,在这些场景中神经科医生或放射科医生可能需要核实他们的患者是否患有出血性中风、梗死及任何其他症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ea/9026481/951aabe66e1b/diagnostics-12-00807-g001.jpg

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