Kim Intae, Minn Dohsik, Kim Suhyun, Kim Jin Kook, Cho Jae Hoon
Seegene Medical Foundation, Busan, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University School of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2022 Aug;15(3):254-263. doi: 10.21053/ceo.2022.00248. Epub 2022 May 26.
Studies on the aeroallergen sensitization status of South Koreans based on large-scale data are lacking.
We analyzed data from 368,156 multiple allergosorbent tests collected by a domestic medical diagnosis company from 3,735 hospitals nationwide from 2018 to 2021. We additionally collected sex, age, and regional data. If the level of an aeroallergen was 0.35 IU/mL or more, the test result for that aeroallergen was defined as positive, and positive cases were defined as those where one aeroallergen was positive. The positive ratio (PR) for aeroallergens was calculated using positive cases.
In total, 347,996 cases were analyzed, excluding cases with missing data. The percentage of positive cases was 56.7%, which was highest in adolescents (74.1%) and lowest in the elderly (47.0%). All four types of mites had high PRs (0.382-0.655), and mold had low PRs (0.023-0.058). Among pollens, the PRs of grasses were generally high (more than 0.14), followed by weeds (approximately 0.10), and the PRs of woods was less than 0.1. For animals, cats and dogs had the highest PRs, at 0.231 and 0.183, respectively. The value for cockroaches was also high, at 0.211. The PRs of indoor aeroallergens, such as mites, molds, and animals, were high in adolescents, and those of pollen and cockroaches were high in the elderly. In Jeju, the PR of Japanese cedars was extremely high (0.222).
Koreans were found to be sensitized to a wide variety of aeroallergens. There were significant differences in sensitization patterns according to age and region.
基于大规模数据的韩国人空气过敏原致敏状况研究尚属空白。
我们分析了一家国内医疗诊断公司在2018年至2021年期间从全国3735家医院收集的368156份多种变应原吸附试验数据。我们还收集了性别、年龄和地区数据。如果空气过敏原水平为0.35 IU/mL或更高，则该空气过敏原的检测结果定义为阳性，阳性病例定义为至少有一种空气过敏原呈阳性的病例。使用阳性病例计算空气过敏原的阳性率（PR）。
总共分析了347996例病例，排除了数据缺失的病例。阳性病例的百分比为56.7%，在青少年中最高（74.1%），在老年人中最低（47.0%）。所有四种螨虫的PR值都很高（0.382 - 0.655），而霉菌的PR值较低（0.023 - 0.058）。在花粉中，草花粉的PR值通常较高（超过0.14），其次是杂草花粉（约0.10），树木花粉的PR值小于0.1。对于动物过敏原，猫和狗的PR值最高，分别为0.231和0.183。蟑螂的PR值也很高，为0.211。青少年中螨虫、霉菌和动物等室内空气过敏原的PR值较高，而老年人中花粉和蟑螂的PR值较高。在济州岛，日本柳杉花粉的PR值极高（0.222）。
发现韩国人对多种空气过敏原敏感。根据年龄和地区，致敏模式存在显著差异。
