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含纳米颗粒的伤口敷料:抗菌与愈合效果

Nanoparticle-Containing Wound Dressing: Antimicrobial and Healing Effects.

作者信息

Yudaev Pavel, Mezhuev Yaroslav, Chistyakov Evgeniy

机构信息

Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russia.

出版信息

Gels. 2022 May 24;8(6):329. doi: 10.3390/gels8060329.

DOI:10.3390/gels8060329
PMID:35735673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9222824/
Abstract

The dressings containing nanoparticles of metals and metal oxides are promising types of materials for wound repair. In such dressings, biocompatible and nontoxic hydrophilic polymers are used as a matrix. In the present review, we take a look at the anti-microbial effect of the nanoparticle-modified wound dressings against various microorganisms and evaluate their healing action. A detailed analysis of 31 sources published in 2021 and 2022 was performed. Furthermore, a trend for development of modern antibacterial wound-healing nanomaterials was shown as exemplified in publications starting from 2018. The review may be helpful for researchers working in the areas of biotechnology, medicine, epidemiology, material science and other fields aimed at the improvement of the quality of life.

摘要

含有金属和金属氧化物纳米颗粒的敷料是用于伤口修复的很有前景的材料类型。在这类敷料中,生物相容性和无毒的亲水性聚合物被用作基质。在本综述中,我们研究了纳米颗粒改性伤口敷料对各种微生物的抗菌作用,并评估了它们的愈合作用。对2021年和2022年发表的31篇文献进行了详细分析。此外,以2018年以来的出版物为例,展示了现代抗菌伤口愈合纳米材料的发展趋势。本综述可能对从事生物技术、医学、流行病学、材料科学和其他旨在提高生活质量领域的研究人员有所帮助。

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