Wang Changqing, Xu Peng, Li Xiaoxu, Zheng Yuhao, Song Zhiming
Department of Sports Medicine, Orthopaedic Center, The First Hospital of Jilin University, Changchun, China.
Front Bioeng Biotechnol. 2022 Dec 23;10:1069932. doi: 10.3389/fbioe.2022.1069932. eCollection 2022.
Infection is one of the most serious complications harmful to human health, which brings a huge burden to human health. Bone infection is one of the most common and serious complications of fracture and orthopaedic surgery. Antibacterial treatment is the premise of bone defect healing. Among all the antibacterial strategies, irritant antibacterial materials have unique advantages and the ability of targeted therapy. In this review, we focus on the research progress of irritating materials, the development of antibacterial materials and their advantages and disadvantages potential applications in bone infection.
感染是危害人类健康最严重的并发症之一,给人类健康带来巨大负担。骨感染是骨折和骨科手术最常见且严重的并发症之一。抗菌治疗是骨缺损愈合的前提。在所有抗菌策略中,刺激性抗菌材料具有独特优势和靶向治疗能力。在本综述中,我们聚焦于刺激性材料的研究进展、抗菌材料的发展及其在骨感染中的优缺点和潜在应用。