Garg Raghav, Vitale Flavia
Department of Neurology, University of Pennsylvania, Philadelphia, USA.
Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, USA.
MRS Bull. 2023;48(3):283-290. doi: 10.1557/s43577-023-00480-0. Epub 2023 Feb 21.
The unique combination of physical and chemical properties of MXenes has propelled a growing number of applications in biomedicine and healthcare. The expanding library of MXenes with tunable properties is paving the way for high-performance, application-specific MXene-based sensing and therapeutic platforms. In this article, we highlight the emerging biomedical applications of MXenes with specific emphasis on bioelectronics, biosensors, tissue engineering, and therapeutics. We present examples of MXenes and their composites enabling novel technological platforms and therapeutic strategies, and elucidate potential avenues for further developments. Finally, we discuss the materials, manufacturing, and regulatory challenges that need to be synergistically addressed for the clinical translation of MXene-based biomedical technologies.
MXenes独特的物理和化学性质组合推动了其在生物医学和医疗保健领域越来越多的应用。具有可调节性质的MXenes库不断扩大，为基于MXene的高性能、特定应用的传感和治疗平台铺平了道路。在本文中，我们重点介绍MXenes在生物医学领域的新兴应用，特别强调生物电子学、生物传感器、组织工程和治疗学。我们展示了MXenes及其复合材料实现新型技术平台和治疗策略的实例，并阐明了进一步发展的潜在途径。最后，我们讨论了基于MXene的生物医学技术临床转化需要协同解决的材料、制造和监管方面的挑战。
