Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Universidade Federal do Pará, Belém, Brazil.
Division of Preventive and Community Dentistry, School of Dentistry, Federal University of Uberlandia, Uberlandia, Minas, Gerais, Brazil.
Front Endocrinol (Lausanne). 2023 Jun 2;14:1167119. doi: 10.3389/fendo.2023.1167119. eCollection 2023.
Obesity is a growing chronic public health problem. The causes of obesity are varied, but food consumption decisions play an important role, especially decisions about what foods to eat and how much to consume. Food consumption decisions are driven, in part, by individual taste perceptions, a fact that can influence eating behavior and, therefore, body mass.
The searches were conducted in the electronic databases PubMed, Web of Science, Scopus, Lilacs, and the grey literature (Google Scholar and Open Grey). The acronym PECO will be used, covering studies with adult humans (P) who have obesity (E) compared to adult humans without obesity (C), having as an outcome the presence of taste alterations (O). After searching, duplicates were removed. The articles were first evaluated by title and abstract, following the inclusion and exclusion criteria; then, the papers were read in full. After the studies were selected, two reviewers extracted the data and assessed the individual risk of bias and control statements for possible confounders and bias consideration. The narrative GRADE system performed the methodological quality assessment using the New Castle Ottawa qualifier and analysis of certainty of evidence.
A total of 3782 records were identified from the database search, of these 19 were considered eligible. Forty percent of the eligible studies show that there was an association between obesity and different taste alterations for different flavors comparing with normal weights adults. In the methodological quality analysis of the nineteen studies, which assesses the risk of bias in the results, fifteen showed good methodological reliability, three showed fair methodological reliability, and one showed low methodological reliability.
Despite methodological limitations, the results of the studies suggest the existence of a association between obesity and taste alterations, but further investigations with more sensitive methodologies are necessary to confirm this hypothesis.
https://osf.io/9vg4h/, identifier 9vg4h.
肥胖是一个日益严重的慢性公共卫生问题。肥胖的原因多种多样，但食物消费决策起着重要作用，尤其是关于吃什么和吃多少的决策。食物消费决策部分受个人味觉感知的驱动，这一事实会影响饮食行为，从而影响体重。
在电子数据库 PubMed、Web of Science、Scopus、Lilacs 和灰色文献（Google Scholar 和 Open Grey）中进行了检索。将使用首字母缩略词 PECO，涵盖患有肥胖症的成年人类（P）与没有肥胖症的成年人类（C）进行比较的研究，其结果为味觉改变（O）的存在。搜索后，去除重复项。首先根据标题和摘要评估文章，遵循纳入和排除标准；然后，全文阅读。选择研究后，两名评审员提取数据，并评估个体偏倚风险和对可能混杂因素和偏倚考虑的控制陈述。叙述性 GRADE 系统使用纽卡斯尔渥太华分级法和证据确定性分析对方法学质量进行评估。
从数据库搜索中确定了 3782 条记录，其中 19 条被认为符合条件。40%的合格研究表明，肥胖与不同口味的不同味觉改变有关，与正常体重的成年人相比。在对 19 项研究进行结果偏倚风险分析的方法学质量评估中，有 15 项显示出良好的方法学可靠性，3 项显示出中等方法学可靠性，1 项显示出低方法学可靠性。
尽管存在方法学限制，但这些研究结果表明肥胖与味觉改变之间存在关联，但需要进一步进行更敏感的方法学研究来证实这一假设。
https://osf.io/9vg4h/，标识符 9vg4h。
