• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

基于氧化石墨烯荧光猝灭效应的生物传感系统

Biosensing Systems Based on Graphene Oxide Fluorescence Quenching Effect.

作者信息

Battisti Antonella, Samal Sangram Keshari, Puppi Dario

机构信息

NEST, Istituto Nanoscienze-CNR and Scuola Normale Superiore, p.zza San Silvestro 12, I-56127 Pisa, Italy.

Laboratory of Biomaterials and Regenerative Medicine for Advanced Therapies, ICMR-RMRC, Bhubaneswar 751023, Odisha, India.

出版信息

Micromachines (Basel). 2023 Jul 28;14(8):1522. doi: 10.3390/mi14081522.

DOI:10.3390/mi14081522
PMID:37630058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10456591/
Abstract

Graphene oxide (GO) is a versatile material obtained by the strong oxidation of graphite. Among its peculiar properties, there is the outstanding ability to significantly alter the fluorescence of many common fluorophores and dyes. This property has been exploited in the design of novel switch-ON and switch-OFF fluorescence biosensing platforms for the detection of a plethora of biomolecules, especially pathological biomarkers and environmental contaminants. Currently, novel advanced strategies are being developed for therapeutic, diagnostic and theranostic approaches to widespread pathologies caused by viral or bacterial agents, as well as to cancer. This work illustrates an overview of the most recent applications of GO-based sensing systems relying on its fluorescence quenching effect.

摘要

氧化石墨烯（GO）是一种通过对石墨进行强氧化而获得的多功能材料。在其独特的性质中，有一项显著特性是能够显著改变许多常见荧光团和染料的荧光。这一特性已被应用于设计新型的开启和关闭荧光生物传感平台，用于检测大量生物分子，特别是病理生物标志物和环境污染物。目前，正在开发新的先进策略，用于针对由病毒或细菌病原体以及癌症引起的广泛疾病的治疗、诊断和治疗诊断方法。这项工作概述了基于GO的传感系统依靠其荧光猝灭效应的最新应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/9af69b761ea8/micromachines-14-01522-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/5a1d686ba545/micromachines-14-01522-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/eec4b23f1aea/micromachines-14-01522-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/cfd01e3eecaf/micromachines-14-01522-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/fc25e254492a/micromachines-14-01522-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/fd36765d338a/micromachines-14-01522-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/912cc4b4ba7d/micromachines-14-01522-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/5d1e37d44a90/micromachines-14-01522-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/9af69b761ea8/micromachines-14-01522-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/5a1d686ba545/micromachines-14-01522-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/eec4b23f1aea/micromachines-14-01522-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/cfd01e3eecaf/micromachines-14-01522-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/fc25e254492a/micromachines-14-01522-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/fd36765d338a/micromachines-14-01522-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/912cc4b4ba7d/micromachines-14-01522-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/5d1e37d44a90/micromachines-14-01522-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fca/10456591/9af69b761ea8/micromachines-14-01522-g008.jpg

相似文献

1
Biosensing Systems Based on Graphene Oxide Fluorescence Quenching Effect.基于氧化石墨烯荧光猝灭效应的生物传感系统
Micromachines (Basel). 2023 Jul 28;14(8):1522. doi: 10.3390/mi14081522.
2
Fluorescent biosensors enabled by graphene and graphene oxide.基于石墨烯和氧化石墨烯的荧光生物传感器。
Biosens Bioelectron. 2017 Mar 15;89(Pt 1):96-106. doi: 10.1016/j.bios.2016.07.030. Epub 2016 Jul 9.
3
Study of Fluorescence Quenching Ability of Graphene Oxide with a Layer of Rigid and Tunable Silica Spacer.具有刚性且可调节二氧化硅间隔层的氧化石墨烯荧光猝灭能力的研究
Langmuir. 2018 Jan 16;34(2):603-611. doi: 10.1021/acs.langmuir.7b03465. Epub 2018 Jan 5.
4
Properties and Applications of Graphene and Its Derivatives in Biosensors for Cancer Detection: A Comprehensive Review.石墨烯及其衍生物在癌症检测生物传感器中的性能及应用：全面综述。
Biosensors (Basel). 2022 Apr 24;12(5):269. doi: 10.3390/bios12050269.
5
Single-probe multistate detection of DNA via aggregation-induced emission on a graphene oxide platform.基于氧化石墨烯平台通过聚集诱导发光实现DNA的单探针多态检测
Acta Biomater. 2017 Mar 1;50:334-343. doi: 10.1016/j.actbio.2016.12.003. Epub 2016 Dec 8.
6
Biosensors based on graphene oxide and its biomedical application.基于氧化石墨烯的生物传感器及其生物医学应用。
Adv Drug Deliv Rev. 2016 Oct 1;105(Pt B):275-287. doi: 10.1016/j.addr.2016.06.001. Epub 2016 Jun 11.
7
Recent Developments in the Applications of GO/rGO-Based Biosensing Platforms for Pesticide Detection.GO/rGO 基生物传感平台在农药检测中的应用的最新进展。
Biosensors (Basel). 2023 Apr 19;13(4):488. doi: 10.3390/bios13040488.
8
Recent progress in the graphene-based biosensing approaches for the detection of Alzheimer's biomarkers.基于石墨烯的用于检测阿尔茨海默病生物标志物的生物传感方法的最新进展。
J Pharm Biomed Anal. 2023 Jan 5;222:115084. doi: 10.1016/j.jpba.2022.115084. Epub 2022 Sep 28.
9
Live cell biosensing platforms using graphene-based hybrid nanomaterials.基于石墨烯杂化纳米材料的活细胞生物传感平台。
Biosens Bioelectron. 2017 Aug 15;94:485-499. doi: 10.1016/j.bios.2017.03.032. Epub 2017 Mar 18.
10
Photoluminescence and Fluorescence Quenching of Graphene Oxide: A Review.氧化石墨烯的光致发光与荧光猝灭：综述
Nanomaterials (Basel). 2022 Jul 17;12(14):2444. doi: 10.3390/nano12142444.

引用本文的文献

1
Fluorescence 'turn-on' sensing of glial fibrillary acidic protein using graphene oxide-quenched copper nanoclusters.利用氧化石墨烯猝灭的铜纳米簇对胶质纤维酸性蛋白进行荧光“开启”传感。
Mikrochim Acta. 2025 Mar 26;192(4):260. doi: 10.1007/s00604-025-07103-2.
2
Research progress of graphene-based nanomaterials in the diagnosis and treatment of head and neck cancer.基于石墨烯纳米材料在头颈部癌症诊断和治疗中的研究进展。
Sci Prog. 2024 Oct-Dec;107(4):368504241291342. doi: 10.1177/00368504241291342.
3
Solid Phase Oligo-DNA Extraction from Complex Medium Using an Aminated Graphene/Nitrocellulose Membrane Hybrid.

本文引用的文献

1
Recent Developments in DNA-Nanotechnology-Powered Biosensors for Zika/Dengue Virus Molecular Diagnostics.用于寨卡病毒/登革热病毒分子诊断的DNA纳米技术驱动的生物传感器的最新进展
Nanomaterials (Basel). 2023 Jan 16;13(2):361. doi: 10.3390/nano13020361.
2
High sensitivity SARS-CoV-2 detection using graphene oxide-multiplex qPCR.利用氧化石墨烯多重 qPCR 进行高灵敏度 SARS-CoV-2 检测。
Anal Chim Acta. 2022 Nov 22;1234:340533. doi: 10.1016/j.aca.2022.340533. Epub 2022 Oct 18.
3
Co-assembled perylene/graphene oxide photosensitive heterobilayer for efficient neuromorphics.
采用氨基化石墨烯/硝酸纤维素膜杂化体从复杂介质中固相提取寡脱氧核苷酸。
Biomolecules. 2024 Mar 19;14(3):366. doi: 10.3390/biom14030366.
共组装苝/氧化石墨烯光敏异质双层结构用于高效神经形态学。
Nat Commun. 2022 Aug 25;13(1):4996. doi: 10.1038/s41467-022-32725-y.
4
Graphene Oxide and Fluorescent-Aptamer-Based Novel Aptasensors for Detection of Metastatic Colorectal Cancer Cells.基于氧化石墨烯和荧光适配体的新型适配体传感器用于检测转移性结肠癌细胞
Polymers (Basel). 2022 Jul 27;14(15):3040. doi: 10.3390/polym14153040.
5
Photoluminescence and Fluorescence Quenching of Graphene Oxide: A Review.氧化石墨烯的光致发光与荧光猝灭：综述
Nanomaterials (Basel). 2022 Jul 17;12(14):2444. doi: 10.3390/nano12142444.
6
Fluorescent Biosensors for the Detection of Viruses Using Graphene and Two-Dimensional Carbon Nanomaterials.基于石墨烯和二维碳纳米材料的病毒荧光生物传感器检测。
Biosensors (Basel). 2022 Jun 27;12(7):460. doi: 10.3390/bios12070460.
7
Dual Detection of Hemagglutinin Proteins of H5N1 and H1N1 Influenza Viruses Based on FRET Combined With DNase I.基于荧光共振能量转移（FRET）结合脱氧核糖核酸酶I（DNase I）对H5N1和H1N1流感病毒血凝素蛋白的双重检测
Front Microbiol. 2022 Jun 30;13:934475. doi: 10.3389/fmicb.2022.934475. eCollection 2022.
8
A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide.一种基于上转换纳米颗粒和氧化石墨烯的新型冠状病毒传感器。
RSC Adv. 2022 Jun 22;12(29):18445-18449. doi: 10.1039/d2ra03599e.
9
An ultrasensitive fluorescent aptasensor for detection of cancer marker proteins based on graphene oxide-ssDNA.一种基于氧化石墨烯-单链DNA的用于检测癌症标志物蛋白的超灵敏荧光适配体传感器。
RSC Adv. 2018 Dec 7;8(72):41143-41149. doi: 10.1039/c8ra08078j.
10
Development of a fluorescence assay for highly sensitive detection of based on an aptamer-carbon dots/graphene oxide system.基于适体-碳点/氧化石墨烯体系的用于高灵敏检测[具体物质未给出]的荧光分析方法的开发。
RSC Adv. 2018 Sep 19;8(57):32454-32460. doi: 10.1039/c8ra04819c. eCollection 2018 Sep 18.