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鼠伤寒血清型亚种在一只猫身上引发了肾盂肾炎，并疑似导致多灶性肌炎。

subspecies serotype Typhimurium induced pyelonephritis and suspected multifocal myositis in a cat.

作者信息

Wilson Remon, Barrs Vanessa R

机构信息

Queensland Veterinary Specialists, North Lakes, QLD, Australia.

Department of Veterinary Clinical Sciences, Jockey Club College of Veterinary Medicine and Life Sciences, and Centre for Animal Health and Welfare, City University of Hong Kong, Kowloon Tong, Hong Kong, SAR China.

出版信息

JFMS Open Rep. 2024 Jan 31;10(1):20551169231221951. doi: 10.1177/20551169231221951. eCollection 2024 Jan-Jun.

DOI:10.1177/20551169231221951
PMID:38304754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10832421/
Abstract

CASE SUMMARY

A 2-year-old male neutered domestic shorthair cat presented with an acute onset of muscular pain, ataxia and fever. Serological tests for IgM and IgG, cryptococcal antigen, feline immune deficiency virus antibody and feline leukaemia virus antigen were all negative. Brain and spinal MRI showed evidence of myositis and bilateral renal parenchymal abnormalities and pyelectasis. subspecies serotype Typhimurium 1,4, [5],12:i:1,2 was isolated from urine and was susceptible to amoxycillin, amoxycillin-clavulanic acid, enrofloxacin and trimethoprim-sulfonamide. All clinical signs resolved after a 2-week treatment course with oral amoxycillin-clavulanate. A repeat urine culture 7 days after completing the antimicrobial course was negative.

RELEVANCE AND NOVEL INFORMATION

Infection with species is uncommon in cats and has not previously been reported in association with pyelonephritis or generalised myositis. The importance of performing urine culture in the initial diagnostic investigation of cats with pyrexia is highlighted in this case report.

摘要

病例摘要

一只2岁已绝育的雄性家养短毛猫出现急性肌肉疼痛、共济失调和发热症状。IgM和IgG、隐球菌抗原、猫免疫缺陷病毒抗体及猫白血病病毒抗原的血清学检测均为阴性。脑部和脊髓的MRI显示有肌炎以及双侧肾实质异常和肾盂扩张的迹象。从尿液中分离出鼠伤寒沙门氏菌1,4,[5],12:i:1,2亚种血清型，该菌对阿莫西林、阿莫西林-克拉维酸、恩诺沙星和甲氧苄啶-磺胺甲恶唑敏感。口服阿莫西林-克拉维酸治疗2周后所有临床症状均消失。抗菌疗程结束7天后复查尿培养结果为阴性。

相关性及新信息

该菌感染在猫中并不常见，此前未有与肾盂肾炎或全身性肌炎相关的报道。本病例报告强调了在对发热猫进行初步诊断检查时进行尿培养的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d66e/10832421/738995bb499c/10.1177_20551169231221951-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d66e/10832421/508ca4241c92/10.1177_20551169231221951-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d66e/10832421/d16ab5ed2ebd/10.1177_20551169231221951-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d66e/10832421/738995bb499c/10.1177_20551169231221951-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d66e/10832421/508ca4241c92/10.1177_20551169231221951-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d66e/10832421/d16ab5ed2ebd/10.1177_20551169231221951-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d66e/10832421/738995bb499c/10.1177_20551169231221951-fig3.jpg

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