人类铁蛋白“H”亚基的基因存在于多条人类染色体上。
Genes for the 'H' subunit of human ferritin are present on a number of human chromosomes.
作者信息
Cragg S J, Drysdale J, Worwood M
出版信息
Hum Genet. 1985;71(2):108-12. doi: 10.1007/BF00283363.
PMID:3862645
Abstract
DNA has been extracted from hamster-human and mouse-human hybrid cell lines, restricted with EcoRI, and hybridised to a probe for the H subunit of human ferritin, pDBR2. Sequences highly homologous to this probe have been found on at least eight human chromosomes: 1, 2, 3, 6p21----6cen, 11, 14, 20, and Xq23-25----Xqter. Only the gene on chromosome 11 appears to be expressed in these hybrids.
摘要
已从仓鼠 - 人及小鼠 - 人杂交细胞系中提取DNA，用EcoRI进行酶切，并与人类铁蛋白H亚基的探针pDBR2杂交。在至少8条人类染色体上发现了与该探针高度同源的序列：1号、2号、3号、6号染色体短臂2区1带至6号染色体着丝粒、11号、14号、20号以及X染色体长臂2区3带至2区5带至X染色体末端。在这些杂交细胞系中，似乎只有11号染色体上的基因会表达。
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