Bioresource Technology Division, School of Industrial Technology, Universiti Sains Malaysia, Gelugor, Malaysia.
Phytochemistry and Phytotechnology Research Group (PhytoRG), Universiti Sains Malaysia, Gelugor, Malaysia.
J Sep Sci. 2024 Aug;47(15):e2400372. doi: 10.1002/jssc.202400372.
The purification of flavonoids using the macroporous polymer resin method has gained attention in recent years due to its simplicity, precision, cost-effectiveness, and the ability to separate flavonoids from other constituents. Several studies have been conducted to investigate the efficiency and effectiveness of macroporous polymer resin in purifying flavonoids from various plant sources. This review aims to evaluate the existing literature on macroporous polymer resin purification of flavonoids and provide a comprehensive analysis of the current research trends and advancements in this field. It also highlights the importance of optimizing the adsorption parameters and conditions such as resin type, resin concentration, pH, and temperature for efficient purification of flavonoids using macroporous polymer resin. The key findings of this review reveal that macroporous resins with weak polarity, large surface areas, and pore diameters have a stronger adsorption capacity for flavonoids compared to polar resins. Furthermore, ultrasonic-solvent assisted extraction often combines with macroporous resin for effective the extraction and purification of flavonoids.
近年来，由于大孔聚合物树脂法具有简单、精确、经济高效以及能够从其他成分中分离黄酮类化合物的特点，因此受到了关注。已经进行了多项研究来探讨大孔聚合物树脂从各种植物来源中纯化黄酮类化合物的效率和效果。本综述旨在评估有关大孔聚合物树脂纯化黄酮类化合物的现有文献，并对该领域的当前研究趋势和进展进行全面分析。它还强调了优化吸附参数和条件（如树脂类型、树脂浓度、pH 值和温度）的重要性，以便使用大孔聚合物树脂有效地纯化黄酮类化合物。本综述的主要发现表明，与极性树脂相比，具有弱极性、大表面积和孔径的大孔树脂对黄酮类化合物具有更强的吸附能力。此外，超声-溶剂辅助提取通常与大孔树脂结合使用，以有效地提取和纯化黄酮类化合物。
