von Wendt L, Rantakallio P, Saukkonen A L, Mäkinen H
Eur J Pediatr. 1985 Jul;144(2):149-51. doi: 10.1007/BF00451901.
A 1 year birth cohort in the provinces of Oulu and Lapland in the Northern part of Finland consisted of 12058 live-born infants, this being 96% of all children born in 1966 in this area. Information on morbidity up to the age of 14 years was collected prospectively by means of questionnaires, special examinations and from national and regional registers of hospital admissions and social services contacts. The total number of children with epilepsy, defined as the occurrence of at least one afebrile epileptic seizure, was 208, 113 boys and 95 girls. The cumulative incidences for epilepsy up to the age of 14 years was 17.3 per 1000. Primary generalised epilepsy was present in 63% and partial seizures in 37%. At least one additional handicapping condition, such as cerebral palsy, mental retardation, and visual or auditory defect was present in 74 children (35.5%). Mental retardation was the most frequent additional handicap, being present in 28%, whereas 16% of the children had cerebral palsy. A total of 75% of the children were able to attend an ordinary school. The high frequency of epilepsy in this study, as compared to other studies, is explained by the cumulative registration of the cases and a high degree of ascertainment of cases with epilepsy.
芬兰北部奥卢省和拉普兰省一个为期1年的出生队列包含12058名活产婴儿，占该地区1966年出生的所有儿童的96%。通过问卷调查、专项检查以及国家和地区的医院入院登记和社会服务接触记录，前瞻性收集了这些儿童14岁之前的发病信息。癫痫的定义为至少发生一次无热惊厥，癫痫患儿总数为208名，其中男孩113名，女孩95名。14岁之前癫痫的累积发病率为每1000人中有17.3例。原发性全身性癫痫占63%，部分性发作占37%。74名儿童（35.5%）至少还存在一种其他致残状况，如脑瘫、智力迟钝以及视觉或听觉缺陷。智力迟钝是最常见的其他致残情况，占28%，而16%的儿童患有脑瘫。共有75%的儿童能够进入普通学校就读。与其他研究相比，本研究中癫痫的高发病率是由于病例的累积登记以及癫痫病例的高度确诊率所致。
