豚鼠迟发型超敏反应及对空气传播型结核病的免疫力。
Delayed-type hypersensitivity and immunity against aerogenic tuberculosis in guinea pigs.
作者信息
Reggiardo Z, Middlebrook G
出版信息
Infect Immun. 1974 May;9(5):815-20. doi: 10.1128/iai.9.5.815-820.1974.
Abstract
In experiments described herein, it was observed that guinea pigs with delayed-type hypersensitivity to tuberculoproteins under various experimental conditions, with or without passive transfer of serum from immune donors, manifested no acquired immunity against aerogenically induced tuberculosis. These results are discussed in relation to the previous observations of other investigators and to the general problem of cellular hypersensitivity and immunity against facultative intracellular bacteria.
摘要
在本文所述的实验中，观察到在各种实验条件下，对结核蛋白有迟发型超敏反应的豚鼠，无论有无来自免疫供体血清的被动转移，均未表现出对气溶胶诱导的结核病的获得性免疫。结合其他研究者先前的观察结果以及细胞超敏反应和针对兼性胞内细菌的免疫这一普遍问题，对这些结果进行了讨论。
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