新型抗生素BN - 227和BN - 227 - F的研究。I. 分类学、分离与特性鉴定
Studies on antibiotics BN-227 and BN-227-F, new antibiotics. I. Taxonomy, isolation and characterization.
作者信息
Itoh J, Miyadoh S, Takahasi S, Amano S, Ezaki N, Yamada Y
出版信息
J Antibiot (Tokyo). 1979 Nov;32(11):1089-95. doi: 10.7164/antibiotics.32.1089.
The two new antibiotics, BN-227 and BN-227-F, were isolated from the fermentation broth of Pseudomonas sp. BN-227. BN-227 has a molecular formula C7H9NO3, and melts at 115 degrees C. BN-227-F has a molecular formula C21H24N3O9Fe, and melts at 156 degrees C. BN-227-F is a chelate compound consisting of three similar ligands (antibiotic BN-227) and ferric ion. The two antibiotics have antimicrobial activity against Gram-positive and Gram-negative bacteria.
两种新型抗生素BN - 227和BN - 227 - F是从假单胞菌属BN - 227的发酵液中分离出来的。BN - 227的分子式为C7H9NO3，熔点为115摄氏度。BN - 227 - F的分子式为C21H24N3O9Fe，熔点为156摄氏度。BN - 227 - F是一种由三个相似配体（抗生素BN - 227）和铁离子组成的螯合物。这两种抗生素对革兰氏阳性菌和革兰氏阴性菌均具有抗菌活性。
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