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Binding of mercury and selenium in subcellular fractions of rat liver and kidneys following separate and joint administration.

作者信息

Komsta-Szumska E, Chmielnicka J

出版信息

Arch Toxicol. 1977 Sep 28;38(3):217-28. doi: 10.1007/BF00293656.

DOI:10.1007/BF00293656
PMID:578725
Abstract

The distribution of mercury and selenium has been examined in subcellular fractions of rat liver and kidneys in prolonged exposure to HgCl2 and Na2SeO3 administered separately and simultaneously. The molar ratio of mercury and selenium concentrations in subcellular fractions of the organs examined varied considerably. Selenium displaced mercury from the soluble kidney fraction bound mainly with metallothionein to the nonhistone protein fraction of liver nuclei. The Hg-stimulated biosynthesis of metallothionein has been eliminated under the influence of selenium.

摘要

相似文献

1
Binding of mercury and selenium in subcellular fractions of rat liver and kidneys following separate and joint administration.
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引用本文的文献

1
Variation of the level of mercury and metallothionein in the kidneys and liver of rats with time of exposure to sodium selenite.随着暴露于亚硒酸钠时间的变化，大鼠肾脏和肝脏中的汞和金属硫蛋白水平的变化。
Biol Trace Elem Res. 1980 Jun;2(2):109-20. doi: 10.1007/BF02798590.
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Mercury and selenium distribution in human kidney cortex.人体肾皮质中汞和硒的分布
Biol Trace Elem Res. 1994 Mar;40(3):255-65. doi: 10.1007/BF02950798.
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Mercury and selenium content and chemical form in fish muscle.鱼肉中汞和硒的含量及化学形态

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The protective effect of small amounts of selenite in sublimate intoxication.少量亚硒酸盐在升汞中毒中的保护作用。
Experientia. 1967 Feb 15;23(2):142-3. doi: 10.1007/BF02135970.
3
Isolation and some properties of human metallothionein.人金属硫蛋白的分离及某些特性
Arch Environ Contam Toxicol. 1981;10(3):305-19. doi: 10.1007/BF01055632.
4
Chemical form and distribution of mercury and selenium in eggs from chickens fed mercury-contaminated grain.
Bull Environ Contam Toxicol. 1981 Apr;26(4):472-8. doi: 10.1007/BF01622122.
5
Uptake and binding of cadmium and mercury to metallothionein in rat hepatocyte primary cultures.镉和汞在大鼠肝细胞原代培养物中对金属硫蛋白的摄取与结合
Biochem J. 1982 Nov 15;208(2):465-72. doi: 10.1042/bj2080465.
6
Interaction of alkylmercuric compounds with sodium selenite. I. Metabolism of ethylmercuric chloride administered alone and in combination with sodium selenite in rats.烷基汞化合物与亚硒酸钠的相互作用。I. 大鼠单独及与亚硒酸钠联合给予氯化乙基汞后的代谢情况
Environ Health Perspect. 1981 Jun;39:131-42. doi: 10.1289/ehp.39-1568742.
7
The effect of methylmercury on the distribution and excretion of selenium by the guinea pig.甲基汞对豚鼠体内硒分布和排泄的影响。
Arch Toxicol. 1983 Dec;54(4):303-10. doi: 10.1007/BF01234483.
8
Selenite toxicity and mercury-selenium interactions in juvenile fish.幼鱼中的亚硒酸盐毒性及汞-硒相互作用
Arch Environ Contam Toxicol. 1983 Jul;12(4):405-13. doi: 10.1007/BF01057583.
9
Effect of interaction between 65Zn, mercury and selenium in rats (retention, metallothionein, endogenous copper).65锌、汞和硒之间的相互作用对大鼠的影响（潴留、金属硫蛋白、内源性铜）
Arch Toxicol. 1983 Jun;53(2):165-75. doi: 10.1007/BF00302724.
10
Interaction of alkylmercuric compounds with sodium selenite. II. Metabolism of methylmercuric chloride administered alone and in combination with sodium selenite in rats.烷基汞化合物与亚硒酸钠的相互作用。II. 单独及与亚硒酸钠联合给予大鼠氯化甲基汞后的代谢情况
Environ Health Perspect. 1985 May;60:411-21. doi: 10.1289/ehp.60-1568548.
Biochemistry. 1966 May;5(5):1768-77. doi: 10.1021/bi00869a046.
4
Effects of arsenic, mercury, thallium, and lead on selenium metabolism in rats.砷、汞、铊和铅对大鼠硒代谢的影响。
Toxicol Appl Pharmacol. 1969 Mar;14(2):308-14. doi: 10.1016/0041-008x(69)90112-4.
5
Enzymatic properties of the inner and outer membranes of rat liver mitochondria.大鼠肝脏线粒体内膜和外膜的酶学特性
J Cell Biol. 1968 Jul;38(1):158-75. doi: 10.1083/jcb.38.1.158.
6
Binding of mercury in the rat kidney by metallothionein.金属硫蛋白对大鼠肾脏中汞的结合作用。
Toxicol Appl Pharmacol. 1970 May;16(3):754-63. doi: 10.1016/0041-008x(70)90081-5.
7
[Effect of sodium selenite, sodium tellurite and sodium sulfite on retention and distribution of mercury in mice].[亚硒酸钠、亚碲酸钠和亚硫酸钠对小鼠体内汞潴留及分布的影响]
Arch Toxikol. 1969;24(3):296-305.
8
Effect of selenite on the toxicity of dietary methyl mercury and mercuric chloride in the rat.亚硒酸盐对大鼠膳食甲基汞和氯化汞毒性的影响。
J Nutr. 1974 May;104(5):638-47. doi: 10.1093/jn/104.5.638.
9
Selenite-induced binding of inorganic mercury in blood and other tissues in the rat.亚硒酸盐诱导大鼠血液及其他组织中无机汞的结合。
Res Commun Chem Pathol Pharmacol. 1974 Mar;7(3):593-603.
10
Reversal of selenium toxicity in chicks by mercury, copper, and cadmium.汞、铜和镉对雏鸡硒中毒的逆转作用。
J Nutr. 1974 May;104(5):593-8. doi: 10.1093/jn/104.5.593.