两种粒子类型在牛轮状病毒形态发生中的作用。
Role of two particle types in bovine rotavirus morphogenesis.
作者信息
Clark S M, Spendlove R S, Barnett B B
出版信息
J Virol. 1980 Apr;34(1):272-6. doi: 10.1128/JVI.34.1.272-276.1980.
Abstract
The involvement of light (L) and dense (D) bovine rotavirus particle types during virus replication has been studied. It was found that infectious parental L virions are uncoated in vivo to a particle similar to native D particles. Differences in the rate of synthesis and relative yields of L and D particles in MDBK and MA-104 cells have been detected. Results from pulse-chase labeling experiments indicate that D particles serve as morphogenic precursors to the complete L virion.
摘要
对轻型（L）和重型（D）牛轮状病毒颗粒类型在病毒复制过程中的参与情况进行了研究。发现有感染性的亲代L病毒粒子在体内脱壳形成类似于天然D粒子的颗粒。已检测到MDBK和MA - 104细胞中L和D粒子的合成速率及相对产量的差异。脉冲追踪标记实验结果表明，D粒子是完整L病毒粒子的形态发生前体。
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