Kutsuzawa T, Konno T, Suzuki H, Kapikian A Z, Ebina T, Ishida N
J Clin Microbiol. 1982 Oct;16(4):727-30. doi: 10.1128/jcm.16.4.727-730.1982.
One strain of human rotavirus subgroup 1 (KUN) and one strain of subgroup 2 (MO) were isolated with the MA104 cell line, a fetal rhesus monkey kidney cell line. Their subgroup specificities and RNA patterns were identical to those of rotaviruses present in stools before cultivation. Distinct cytopathic effects consisting of obscure cell boundaries, cell fusion, cell rounding, cell detachment, and lytic foci were recognized at passage 3 of MO and passage 6 of KUN. No differences in cytopathic changes were found between the two isolates.
一株人轮状病毒1型（KUN）和一株2型（MO）通过MA104细胞系（一种恒河猴胎儿肾细胞系）分离得到。它们的亚组特异性和RNA模式与培养前粪便中存在的轮状病毒相同。在MO传代3次和KUN传代6次时，观察到明显的细胞病变效应，包括细胞边界模糊、细胞融合、细胞变圆、细胞脱落和溶细胞灶。两种分离株之间在细胞病变变化方面未发现差异。
