细胞因子与风湿性疾病的慢性炎症。II. 滑液中白细胞介素-2的存在情况。
Cytokines and the chronic inflammation of rheumatic disease. II. The presence of interleukin-2 in synovial fluids.
作者信息
Nouri A M, Panayi G S, Goodman S M
出版信息
Clin Exp Immunol. 1984 Nov;58(2):402-9.
Abstract
Sera and synovial fluids from patients with a variety of rheumatic diseases were assayed for interleukin-2 (IL-2) activity in a system utilizing the proliferative response of cultured human phytohaemagglutinin (PHA) T cell blasts. The synovial fluids from 14 rheumatoid arthritis, eight ankylosing spondylitis, three psoriatic arthritis and 11 osteoarthritis patients, all showed IL-2 activity. The amounts of IL-2 present in the fluids from different diseases were compared and ranged from 4.2 to 140.0 units/ml.
摘要
利用培养的人植物血凝素（PHA）T细胞母细胞的增殖反应系统，对患有各种风湿性疾病患者的血清和滑液进行白细胞介素-2（IL-2）活性检测。14例类风湿性关节炎、8例强直性脊柱炎、3例银屑病关节炎和11例骨关节炎患者的滑液均显示出IL-2活性。对不同疾病患者滑液中IL-2的含量进行了比较，范围为4.2至140.0单位/毫升。
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