Partridge J W, Flewett T H, Whitehead J E
Br Med J (Clin Res Ed). 1981 Jan 17;282(6259):187-8. doi: 10.1136/bmj.282.6259.187.
A woman who had had high titres of rubella antibodies some months before she became pregnant gave birth to an infant in whom congenital rubella was confirmed at 4 months. Rubella haemagglutination inhibition tests, complement fixation tests, and immunofluorescence tests with anti-human IgG were carried out on sera from the mother. Rubella antibody titres in sera obtained in March 1971, seven and a half months before conception, were equivalent to 400 units, which is usually taken as indicating good immunity. Rubella virus was isolated from the baby's nose and throat in July 1973 but was not isolated from a cervical swab taken from the mother in December 1973; tests of her immunological competence did not show any definite abnormality. The presence of high levels of rubella haemagglutination inhibition antibodies does not invariably confer immunity or exclude the possibility of congenital rubella in a subsequent pregnancy.
一名妇女在怀孕前几个月风疹抗体效价很高，她生下了一个婴儿，该婴儿在4个月时被确诊患有先天性风疹。对母亲的血清进行了风疹血凝抑制试验、补体结合试验以及抗人IgG免疫荧光试验。1971年3月，即受孕前七个半月采集的血清中风疹抗体效价相当于400单位，这通常被视为表明有良好的免疫力。1973年7月从婴儿的鼻和咽喉中分离出风疹病毒，但1973年12月从母亲宫颈拭子中未分离出该病毒；对她免疫能力的检测未显示任何明确异常。风疹血凝抑制抗体水平高并不一定能赋予免疫力，也不能排除随后妊娠时发生先天性风疹的可能性。
