用于分析一级结构同源性的矩阵程序。
Matrix program to analyze primary structure homology.
作者信息
Novotny J
出版信息
Nucleic Acids Res. 1982 Jan 11;10(1):127-31. doi: 10.1093/nar/10.1.127.
Abstract
A FORTRAN program to analyze homology of letter strings (nucleotide or amino acid sequences) and to display the result in the form of a dot matrix is presented. The program is generally usable, user-friendly and has a number of options (filtering, "fudging," i.e., consideration of groups of homologous residues, and screening, i.e., display of only particular groups of residues) which greatly potentiate its analytical power.
摘要
本文展示了一个FORTRAN程序，用于分析字母串（核苷酸或氨基酸序列）的同源性，并以点矩阵的形式显示结果。该程序通用性强、用户友好，具有多种选项（过滤、“模糊处理”，即考虑同源残基组，以及筛选，即仅显示特定残基组），极大地增强了其分析能力。
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本文引用的文献
1
Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.重链可变区对NPb抗体家族的贡献：γ2a可变区中明显的体细胞突变。
Cell. 1981 Jun;24(3):625-37. doi: 10.1016/0092-8674(81)90089-1.
2
Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes.三个编码小鼠移植抗原的cDNA克隆：与免疫球蛋白基因的同源性
Cell. 1981 Apr;24(1):125-34. doi: 10.1016/0092-8674(81)90508-0.
3
Structure of the constant and 3' untranslated regions of the murine Balb/c gamma 2a heavy chain messenger RNA.小鼠Balb/cγ2a重链信使核糖核酸的恒定区和3'非翻译区的结构
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4
Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.克隆的人类和小鼠κ免疫球蛋白恒定区和J区基因在功能片段上保持同源性。
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