Cant A, Marsden R A, Kilshaw P J
Br Med J (Clin Res Ed). 1985 Oct 5;291(6500):932-5. doi: 10.1136/bmj.291.6500.932.
Forty nine eczematous infants who were still solely and exclusively breast fed and who had never received anything but breast milk were studied for evidence of sensitisation to foods. Thirty four similar infants without eczema formed a control group. The eczematous infants were divided into three groups according to clinical criteria: (1) definite atopic eczema; (2) possible atopic eczema; (3) atopic eczema unlikely. Twenty three infants showed cutaneous hypersensitivity to foods, usually egg and cows' milk. Seven of 14 infants in group 1 and nine of 20 in group 2 were sensitised compared with four of 15 in group 3 and three of 34 controls (p less than 0.01). Ovalbumin was detected in breast milk from 14 of 19 mothers tested after ingestion of egg, the concentrations being the same for mothers feeding eczematous and normal infants. Breast fed babies developing eczema may be sensitised by foods eaten by their mothers.
对49名仍完全以母乳喂养且除母乳外未接受过任何其他食物的患湿疹婴儿进行研究，以寻找其对食物过敏的证据。34名未患湿疹的类似婴儿组成对照组。根据临床标准，患湿疹婴儿被分为三组：（1）确诊为特应性湿疹；（2）可能为特应性湿疹；（3）不太可能为特应性湿疹。23名婴儿对食物表现出皮肤过敏，通常是对鸡蛋和牛奶过敏。第1组14名婴儿中有7名、第2组20名婴儿中有9名出现过敏，而第3组15名婴儿中有4名、34名对照组婴儿中有3名出现过敏（p<0.01）。在摄入鸡蛋后接受检测的19名母亲中，有14名母亲的母乳中检测到卵清蛋白，喂养患湿疹婴儿和正常婴儿的母亲母乳中卵清蛋白浓度相同。患湿疹的母乳喂养婴儿可能会因母亲食用的食物而致敏。
