Murray P I
Academic Unit of Ophthalmology, Birmingham and Midland Eye Hospital, UK.
Int Ophthalmol. 1994;18(6):361-2. doi: 10.1007/BF00930316.
A 53-year-old man with Wegener's granulomatosis and a co-existing pituitary adenoma developed bilateral acute retinal necrosis (BARN), probably secondary to varicella-zoster virus (VZV) infection as IgM antibodies were detected in the serum. Intravenous acyclovir and ganciclovir limited the spread of necrosis, but to prevent recurrence he was maintained on oral acyclovir. A left cataract developed 17 months later which was extracted and replaced with a heparin surface modified intraocular lens. Intraocular specimens removed at the time of surgery were analysed by the polymerase chain reaction (PCR) using primers specific for a number of the herpes group of viruses, but no herpesviral DNA could be detected.
一名患有韦格纳肉芽肿病且并存垂体腺瘤的53岁男性发生了双侧急性视网膜坏死（BARN），可能继发于水痘-带状疱疹病毒（VZV）感染，因为血清中检测到IgM抗体。静脉注射阿昔洛韦和更昔洛韦限制了坏死的扩散，但为防止复发，让他持续口服阿昔洛韦。17个月后出现了左眼白内障，进行了摘除并植入了肝素表面改性人工晶状体。手术时取出的眼内标本通过聚合酶链反应（PCR）使用针对多种疱疹病毒组的引物进行分析，但未检测到疱疹病毒DNA。
