Ruo S L, Li Y L, Tong Z, Ma Q R, Liu Z L, Tang Y W, Ye K L, McCormick J B, Fisher-Hoch S P, Xu Z Y
Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333.
J Infect Dis. 1994 Sep;170(3):527-34. doi: 10.1093/infdis/170.3.527.
Residents of two villages in Zhejiang Province, China, were interviewed and serum samples were collected to assess prevalence of hantavirus infection. Antibody prevalence was 12% (219/1811), with a ratio of illness to infection of 1.0:5.4. Seroprevalence increased with age, but no association was found with sex. There was also no evidence of vertical transmission. One year later, 2.3% (30/1325) of seronegative subjects had seroconverted including 2 who had hemorrhagic fever with renal syndrome. Peak incidence of infection occurred in those 15-39 years old. Hantaan was the dominant serotype; Seoul serotype was less common (5:1). Host reservoirs were Apodemus agrarius in agricultural fields and Rattus norvegicus in houses. Risk factors for infection were traces of rat-contaminated food, travel to other areas for farm work, direct rodent contact, camping in grain fields, living in a house on the periphery of a village, stacking straw stacks outside houses, and keeping cats. All may provide exposure to infectious rodent reservoirs.
对中国浙江省两个村庄的居民进行了访谈，并采集了血清样本以评估汉坦病毒感染的流行情况。抗体流行率为12%（219/1811），发病与感染的比例为1.0:5.4。血清阳性率随年龄增长而升高，但未发现与性别有关联。也没有垂直传播的证据。一年后，2.3%（30/1325）的血清阴性受试者出现了血清转化，其中包括2例患肾综合征出血热的患者。感染的高峰发病率出现在15至39岁的人群中。汉滩病毒是主要血清型；汉城血清型较少见（比例为5:1）。宿主储存宿主为农田中的黑线姬鼠和房屋中的褐家鼠。感染的危险因素包括有鼠类污染食物的痕迹、到其他地区从事农活、直接接触啮齿动物、在粮田露营、居住在村庄周边的房屋内、在房屋外堆放稻草垛以及养猫。所有这些都可能使人接触到具有传染性的啮齿动物储存宿主。
