比较头孢克肟和氧氟沙星三日疗法治疗女性单纯性尿路感染的双盲研究。
Double-blind study comparing 3-day regimens of cefixime and ofloxacin in treatment of uncomplicated urinary tract infections in women.
作者信息
Raz R, Rottensterich E, Leshem Y, Tabenkin H
机构信息
Infectious Disease Unit, Central Emek Hospital, Afula, Israel.
出版信息
Antimicrob Agents Chemother. 1994 May;38(5):1176-7. doi: 10.1128/AAC.38.5.1176.
Abstract
This double-blind randomized study compared 3-day regimens of cefixime (400 mg once daily) and ofloxacin (200 mg twice a day) in the treatment of urinary tract infections in women. The respective clinical cure rates for the two groups of women were 89 and 92% after 7 days and 81 and 84% after 4 weeks. The respective microbiological cure rates (free of bacteriuria) for the two groups of women were 83 and 86% after 7 days and 77 and 80% after 28 days. A 3-day cefixime regimen seems to be as efficient as a 3-day ofloxacin regimen in the treatment of uncomplicated cystitis in women.
摘要
这项双盲随机研究比较了头孢克肟（每日一次，400毫克）和氧氟沙星（每日两次，200毫克）的3天疗程在治疗女性尿路感染中的效果。两组女性在7天后的临床治愈率分别为89%和92%，4周后的临床治愈率分别为81%和84%。两组女性在7天后的微生物学治愈率（无菌尿）分别为83%和86%，28天后分别为77%和80%。在治疗女性单纯性膀胱炎方面，3天的头孢克肟疗程似乎与3天的氧氟沙星疗程一样有效。
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