La Vecchia C, Negri E, Franceschi S, Conti E, Montella M, Giacosa A, Falcini A, Decarli A
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Br J Cancer. 1997;76(5):675-7. doi: 10.1038/bjc.1997.444.
The relationship between aspirin use and colorectal cancer risk was examined by a case-control study in Italy. Regular aspirin use was reported by only 47 (3.5%) cases and 77 (4.1%) control subjects, giving a multivariate odds ratio (OR) of 0.7 (95% CI 0.5-1.0) after allowance for education, physical exercise and selected dietary factors.
意大利的一项病例对照研究对阿司匹林使用与结直肠癌风险之间的关系进行了调查。仅47名（3.5%）病例和77名（4.1%）对照受试者报告经常使用阿司匹林，在对教育程度、体育锻炼和选定的饮食因素进行校正后，多变量比值比（OR）为0.7（95%可信区间0.5 - 1.0）。
