Mai Truong Tuyet, Thu Nghiem Nguyet, Tien Pham Gia, Van Chuyen Nguyen
Department of Food and Nutrition, Japan Women's University, Tokyo 112-8681, Japan.
J Nutr Sci Vitaminol (Tokyo). 2007 Jun;53(3):267-76. doi: 10.3177/jnsv.53.267.
The prevention and treatment of non-communicable diseases by using the beneficial biological effects of polyphenolic plants have attracted increasing interest from nutritional scientists. The a-glucosidase inhibitory and antioxidant activities of aqueous and methanolic extracts from 28 common Vietnamese edible plants, comprising 4 groups (plants used for making drinks, edible wild vegetables, herbs, and dark green vegetables), were investigated in vitro. The polyphenol contents of these extracts were determined by the Folin-Ciocalteu method and calculated as catechin equivalents. The extracts from plants used for making drinks showed the highest activities for both a-glucosidase inhibition and as antioxidants, followed by edible wild vegetables, herbs, and dark green vegetables. Positive relationships among alpha-glucosidase inhibitory activities, antioxidant activities and polyphenol contents of these 28 edible plants were found in both aqueous and methanolic extracts. Four new promising materials that are similar to or better than guava leaf extract, including Syzygium zeylanicum, Cleistocalyx operculatus, Horsfieldia amygdalina and Careya arborea demonstrated high alpha-glucosidase inhibitory activity (93, 76, 68 and 67%, respectively) at the final concentration of 0.8 mg lyophilized material/mL solution and antioxidant activity (85, 87, 78 and 80%, respectively) at the final concentration of 30 pg lyophilized material/mL solution. These four edible plants contained significantly high polyphenol contents (equivalent to 251.7, 146.6, 136.6 and 168.6 mg of catechin/g dry weight, respectively). Thus, these four materials might be possible new sources of a-glucosidase inhibition and antioxidants suitable for use as functional foods in the future.
利用多酚类植物的有益生物学效应来预防和治疗非传染性疾病，已引起营养科学家越来越浓厚的兴趣。对越南28种常见食用植物（包括用于制作饮品的植物、可食用野菜、草药和深绿色蔬菜4类）的水提取物和甲醇提取物的α-葡萄糖苷酶抑制活性及抗氧化活性进行了体外研究。这些提取物中的多酚含量采用福林-酚法测定，并以儿茶素当量计算。用于制作饮品的植物提取物在α-葡萄糖苷酶抑制和抗氧化方面均表现出最高活性，其次是可食用野菜、草药和深绿色蔬菜。在水提取物和甲醇提取物中，这28种食用植物的α-葡萄糖苷酶抑制活性、抗氧化活性和多酚含量之间均存在正相关关系。四种新的有前景的材料，与番石榴叶提取物相似或优于番石榴叶提取物，包括锡兰蒲桃、水翁、滇南风吹楠和八宝树，在冻干材料终浓度为0.8mg/mL溶液时表现出较高的α-葡萄糖苷酶抑制活性（分别为93%、76%、68%和67%），在冻干材料终浓度为30μg/mL溶液时表现出抗氧化活性（分别为85%、87%、78%和80%）。这四种可食用植物含有显著高的多酚含量（分别相当于251.7、146.6、136.6和168.6mg儿茶素/g干重）。因此，这四种材料可能是未来适合用作功能性食品的α-葡萄糖苷酶抑制剂和抗氧化剂的新来源。
