Caporali R, Ravelli A, De Gennaro F, Neirotti G, Montecucco C, Martini A
Institute of Medical Pathology, University of Pavia, Italy.
Ann Rheum Dis. 1991 Sep;50(9):599-601. doi: 10.1136/ard.50.9.599.
The prevalence of anticardiolipin antibodies was evaluated in 70 children with juvenile chronic arthritis (JCA), in 25 adult patients with rheumatoid arthritis, in 42 healthy children and in 40 adult controls. Thirty seven (53%) patients with JCA were positive for IgG or IgM anticardiolipin antibodies, or both, and 30 (43%) for IgG anticardiolipin antibodies. In contrast, only seven (28%) adult patients with rheumatoid arthritis presented anticardiolipin antibodies, which were of IgG class in four (16%) cases. IgG anticardiolipin antibodies were negative in all control subjects while IgM anticardiolipin antibodies were detected in two (5%) children and in four (10%) adult controls. No correlations were found in patients with JCA between the presence or titres of anticardiolipin antibodies and various clinical or laboratory variables. No patient with anticardiolipin antibodies showed any feature of the anticardiolipin syndrome.
对70名幼年慢性关节炎（JCA）患儿、25名成年类风湿关节炎患者、42名健康儿童及40名成年对照者进行了抗心磷脂抗体患病率评估。37名（53%）JCA患者的IgG或IgM抗心磷脂抗体呈阳性，或两者均呈阳性，30名（43%）患者的IgG抗心磷脂抗体呈阳性。相比之下，仅7名（28%）成年类风湿关节炎患者存在抗心磷脂抗体，其中4名（16%）患者为IgG类。所有对照者的IgG抗心磷脂抗体均为阴性，而在2名（5%）儿童及4名（10%）成年对照者中检测到IgM抗心磷脂抗体。在JCA患者中，未发现抗心磷脂抗体的存在或滴度与各种临床或实验室变量之间存在相关性。没有抗心磷脂抗体的患者表现出抗心磷脂综合征的任何特征。
