感染尼帕病毒的松鼠猴实验。
Experimental infection of squirrel monkeys with nipah virus.
机构信息
Institut Pasteur, Lyon, France.
出版信息
Emerg Infect Dis. 2010 Mar;16(3):507-10. doi: 10.3201/eid1603.091346.
Abstract
We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys' suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.
摘要
我们用尼帕病毒感染松鼠猴（Saimiri sciureus），以确定它们是否适合作为灵长类动物模型，用于预防和治疗方法的临床前测试。通过静脉注射感染松鼠猴后，它们会出现高死亡率，伴有急性神经和呼吸道疾病以及病毒 RNA 和抗原的产生。
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