海洋细菌灰色链霉菌 M045 的基因组草图，该菌产生具有 pABA 核心结构的新型马努菌素类抗生素。
Draft genome sequence of the marine bacterium Streptomyces griseoaurantiacus M045, which produces novel manumycin-type antibiotics with a pABA core component.
机构信息
Nanjing Agricultural University, Nanjing 210095, China.
出版信息
J Bacteriol. 2011 Jul;193(13):3417-8. doi: 10.1128/JB.05053-11. Epub 2011 May 6.
Abstract
Streptomyces griseoaurantiacus M045, isolated from marine sediment, produces manumycin and chinikomycin antibiotics. Here we present a high-quality draft genome sequence of S. griseoaurantiacus M045, the first marine Streptomyces species to be sequenced and annotated. The genome encodes several gene clusters for biosynthesis of secondary metabolites and has provided insight into genomic islands linking secondary metabolism to functional adaptation in marine S. griseoaurantiacus M045.
摘要
灰色链霉菌 M045 从海洋沉积物中分离得到，可产生马努菌素和奇诺霉素抗生素。本文呈现了灰色链霉菌 M045 的高质量基因组草图序列，这是首个完成测序和注释的海洋链霉菌种。该基因组编码了多个次级代谢产物生物合成基因簇，为基因组岛如何将次级代谢与海洋灰色链霉菌 M045 的功能适应联系起来提供了深入的了解。
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2
Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria.基因组岛将海洋放线菌的次生代谢与功能适应性联系起来。
ISME J. 2009 Oct;3(10):1193-203. doi: 10.1038/ismej.2009.58. Epub 2009 May 28.
3
Developing a new resource for drug discovery: marine actinomycete bacteria.开发一种用于药物发现的新资源：海洋放线菌
Nat Chem Biol. 2006 Dec;2(12):666-73. doi: 10.1038/nchembio841.
4
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models.使用隐马尔可夫模型对原核生物基因组中的基因组岛进行基于分数的预测。
BMC Bioinformatics. 2006 Mar 16;7:142. doi: 10.1186/1471-2105-7-142.
5
From ergot to ansamycins-45 years in biosynthesis.
J Nat Prod. 2006 Jan;69(1):158-69. doi: 10.1021/np058108l.
6
Genome sequencing in microfabricated high-density picolitre reactors.微制造高密度皮升反应器中的基因组测序
Nature. 2005 Sep 15;437(7057):376-80. doi: 10.1038/nature03959. Epub 2005 Jul 31.
7
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J Nat Prod. 2005 Mar;68(3):349-53. doi: 10.1021/np030518r.
8
Marine actinomycete diversity and natural product discovery.海洋放线菌的多样性与天然产物发现
Antonie Van Leeuwenhoek. 2005 Jan;87(1):43-8. doi: 10.1007/s10482-004-6540-1.
9
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10
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Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W390-3. doi: 10.1093/nar/gkh380.
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