Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, MS 39759, USA.
Viruses. 2011 Nov;3(11):2160-91. doi: 10.3390/v3112160. Epub 2011 Nov 8.
Herpesviruses are host specific pathogens that are widespread among vertebrates. Genome sequence data demonstrate that most herpesviruses of fish and amphibians are grouped together (family Alloherpesviridae) and are distantly related to herpesviruses of reptiles, birds and mammals (family Herpesviridae). Yet, many of the biological processes of members of the order Herpesvirales are similar. Among the conserved characteristics are the virion structure, replication process, the ability to establish long term latency and the manipulation of the host immune response. Many of the similar processes may be due to convergent evolution. This overview of identified herpesviruses of fish discusses the diseases that alloherpesviruses cause, the biology of these viruses and the host-pathogen interactions. Much of our knowledge on the biology of Alloherpesvirdae is derived from research with two species: Ictalurid herpesvirus 1 (channel catfish virus) and Cyprinid herpesvirus 3 (koi herpesvirus).
疱疹病毒是宿主特异性病原体，广泛存在于脊椎动物中。基因组序列数据表明，大多数鱼类和两栖类疱疹病毒聚集在一起（Alloherpesviridae 科），与爬行类、鸟类和哺乳类疱疹病毒（Herpesviridae 科）的亲缘关系较远。然而，疱疹病毒目成员的许多生物学过程是相似的。其中保守的特征包括病毒粒子结构、复制过程、建立长期潜伏感染的能力以及对宿主免疫反应的操纵。许多相似的过程可能是由于趋同进化。本文概述了鱼类疱疹病毒，讨论了 alloherpesviruses 引起的疾病、这些病毒的生物学以及宿主-病原体相互作用。我们对 Alloherpesvirdae 生物学的大部分了解都来自于对两个物种的研究：Ictalurid herpesvirus 1（channel catfish virus）和 Cyprinid herpesvirus 3（koi herpesvirus）。
