Richards J C, Hyman R W, Rapp F
J Virol. 1979 Dec;32(3):812-21. doi: 10.1128/JVI.32.3.812-821.1979.
The 32P-labeled DNAs from seven different clinical isolates of human varicella-zoster virus (VZV) were independently digested with five site-specific restriction endonucleases, EcoRI, HindIII, SmaI, BamHI, and AvaI. The digestion products were analyzed by electrophoresis on 0.5% agarose gels followed by autoradiography of the dried gels. Evaluation of the restriction enzyme cleavage patterns revealed small variations among the VZV DNAs. The VZV DNAs were also compared based on their buoyant densities in CsCl. No significant buoyant density differences were detected among the VZV DNAs.
来自七株不同人类水痘带状疱疹病毒（VZV）临床分离株的32P标记DNA，分别用五种位点特异性限制性内切酶EcoRI、HindIII、SmaI、BamHI和AvaI进行消化。消化产物在0.5%琼脂糖凝胶上进行电泳分析，然后对干燥的凝胶进行放射自显影。对限制性酶切图谱的评估显示VZV DNA之间存在微小差异。还根据VZV DNA在CsCl中的浮力密度进行了比较。在VZV DNA之间未检测到显著的浮力密度差异。
