小鼠巨细胞病毒与分离的脾细胞群体的相互作用。
Interaction of murine cytomegalovirus with separated populations of spleen cells.
作者信息
Loh L, Hudson J B
出版信息
Infect Immun. 1979 Dec;26(3):853-60. doi: 10.1128/iai.26.3.853-860.1979.
Abstract
Mouse spleen cultures were infected with murine cytomegalovirus, either before or after separating the cells into various classes, and the growth of virus and production of infectious centers were measured in each cell class. The separation techniques, which were used in various combinations, comprised: adherence to plastic surfaces; adherence to nylon wool columns; gamma irradiation; and treatment with anti-immunoglobulin serum plus complement. The "macrophage population" took up most of the input virus, as shown by autoradiography of spleen cells infected with radioactive virus. These cells formed infectious centers but replicated the virus only transiently. In contrast, the "B-lymphocyte population" contained a minor cell fraction which was permissive for replication. The "T-lymphocyte population" appeared to be nonpermissive for replication and did not produce infectious centers.
摘要
在将小鼠脾脏细胞分为不同类别之前或之后，用鼠巨细胞病毒感染小鼠脾脏培养物，并测定每个细胞类别中病毒的生长情况和感染中心的产生情况。所使用的分离技术以各种组合方式进行，包括：贴附于塑料表面；贴附于尼龙毛柱；γ射线照射；以及用抗免疫球蛋白血清加补体处理。如对感染放射性病毒的脾脏细胞进行放射自显影所示，“巨噬细胞群体”摄取了大部分输入病毒。这些细胞形成感染中心，但仅短暂复制病毒。相比之下，“B淋巴细胞群体”含有一小部分允许病毒复制的细胞。“T淋巴细胞群体”似乎不允许病毒复制，也不产生感染中心。
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本文引用的文献
1
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Am J Clin Pathol. 1971 Mar;55(3):283-90. doi: 10.1093/ajcp/55.3.283.
2
3
A rapid method for the isolation of functional thymus-derived murine lymphocytes.一种分离功能性胸腺来源的小鼠淋巴细胞的快速方法。
Eur J Immunol. 1973 Oct;3(10):645-9. doi: 10.1002/eji.1830031011.
4
Induction of disseminated virulent cytomegalovirus infection by immunosuppression of naturally chronically infected wild mice.通过对自然慢性感染的野生小鼠进行免疫抑制诱导播散性强毒巨细胞病毒感染。
Infect Immun. 1974 Oct;10(4):966-9. doi: 10.1128/iai.10.4.966-969.1974.
5
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7
Infection of adult mouse macrophages in vitro with cytomegalovirus.
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8
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