Departamento de Salud y Rendimiento Humano, Facultad de Ciencias de la Actividad Física y del Deporte-INEF, Universidad Politécnica de Madrid, C/ Martín Fierro, 7, 28040 Madrid, Spain.
QJM. 2013 Sep;106(9):809-21. doi: 10.1093/qjmed/hct089. Epub 2013 May 8.
High prevalence of vitamin D insufficiency (<75 nmol/l) has been previously reported in European adolescents. Vitamin D deficiency has been related to physical fitness and adiposity but it is not clearly known whether this relationship applies to growing children and adolescents.
To determine how body composition and physical fitness are related to 25-hydroxyvitamin D [25(OH)D] concentrations in European adolescents.
The HEalthy Lifestyle in Europe by Nutrition in Adolescence-CSS study was a multi-centre cross-sectional study.
Plasma 25(OH)D, body composition and physical fitness measures were obtained in 1006 European adolescents (470 males) aged 12.5-17.5 years. Stepwise regression and ANCOVA were performed by gender using 25(OH)D as dependent variable, with body composition, physical fitness as independent variables controlling for age, seasonality and latitude.
For males, maximum oxygen consumption (VO2max) (B = 0.189) and body mass index (BMI) (B = -0.124) were independently associated with 25(OH)D concentrations (both P < 0.05). For females, handgrip strength (B = 0.168; P < 0.01) was independently associated with 25(OH)D concentrations. Those adolescents at lower BMI and high fitness score presented significant higher 25(OH)D concentrations than those at lower fitness score in the other BMI groups (P < 0.05).
Cardiorespiratory fitness and upper limbs muscular strength are positively associated with 25(OH)D concentrations in male and female adolescents, respectively. Adiposity in males and low fat free mass in females are related to hypovitaminosis D. The interaction between fitness and BMI has a positive effect on 25(OH)D concentrations. Therapeutic interventions to correct the high rates of vitamin D deficiency in adolescents should consider physical fitness.
先前的研究报告显示，欧洲青少年普遍存在维生素 D 不足（<75nmol/L）的情况。维生素 D 缺乏与身体健康和肥胖有关，但目前尚不清楚这种关系是否适用于正在成长的儿童和青少年。
确定身体成分和身体健康与欧洲青少年 25-羟维生素 D [25(OH)D]浓度之间的关系。
HEalthy Lifestyle in Europe by Nutrition in Adolescence-CSS 研究是一项多中心横断面研究。
在 1006 名年龄在 12.5-17.5 岁的欧洲青少年（470 名男性）中，测量了血浆 25(OH)D、身体成分和身体素质指标。使用 25(OH)D 作为因变量，采用逐步回归和协方差分析（ANCOVA），按性别进行分析，将身体成分和身体素质作为自变量，同时控制年龄、季节性和纬度。
对于男性，最大摄氧量（VO2max）（B=0.189）和体重指数（BMI）（B=-0.124）与 25(OH)D 浓度独立相关（均 P<0.05）。对于女性，握力（B=0.168；P<0.01）与 25(OH)D 浓度独立相关。与其他 BMI 组中低运动能力评分的青少年相比，处于较低 BMI 且高运动能力评分的青少年 25(OH)D 浓度显著更高（P<0.05）。
心肺健康和上肢肌肉力量分别与男性和女性青少年 25(OH)D 浓度呈正相关。男性肥胖和女性体脂含量低与维生素 D 缺乏有关。身体活动和 BMI 之间的相互作用对 25(OH)D 浓度有积极影响。为了纠正青少年维生素 D 缺乏的高发病率，治疗干预措施应考虑身体健康。
