口腔链球菌属交叉反应性多糖抗原（a、d和h型）与单克隆抗体的免疫学研究。
Immunological study of cross-reactive polysaccharide antigens (types a, d, and h) of oral Streptococcus spp. with monoclonal antibodies.
作者信息
Ota F, Kato H, Fukui K
出版信息
Infect Immun. 1987 Jan;55(1):266-8. doi: 10.1128/iai.55.1.266-268.1987.
Abstract
Two monoclonal antibodies against the cross-reactive antigens of S. cricetus (type a) and S. sobrinus (type d) were isolated. Galactose and especially melibiose inhibited the precipitin reaction markedly. Inhibition by melibiose was over 200-fold stronger than that by galactose. This may indicate that galactose-alpha 1, 6-glucose is the predominant antigenic determinant of this cross-reactive antigen. This antigen was also found in S. sobrinus type h strains, but no antigen was found in one type d strain (OMZ176).
摘要
分离出了两种针对仓鼠链球菌（a型）和远缘链球菌（d型）交叉反应抗原的单克隆抗体。半乳糖尤其是蜜二糖显著抑制沉淀反应。蜜二糖的抑制作用比半乳糖强200多倍。这可能表明α-1,6-半乳糖葡萄糖是这种交叉反应抗原的主要抗原决定簇。在远缘链球菌h型菌株中也发现了这种抗原，但在一株d型菌株（OMZ176）中未发现抗原。
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本文引用的文献
1
Demonstration of the etiologic role of streptococci in experimental caries in the hamster.
J Am Dent Assoc. 1960 Jul;61:9-19. doi: 10.14219/jada.archive.1960.0138.
2
Purification and characterization of a rhamnose-containing cell wall antigen of Streptococcus mutans B13 (serotype d).
Infect Immun. 1980 Jan;27(1):150-7. doi: 10.1128/iai.27.1.150-157.1980.
3
Immunochemical characteristics of Streptococcus mutans serotype h carbohydrate antigen.
Microbiol Immunol. 1984;28(4):407-13. doi: 10.1111/j.1348-0421.1984.tb00692.x.
4
The isolation of characterization of Streptococcus mutans serotype h from dental plaque of monkeys (Macaca fascicularis).
J Gen Microbiol. 1981 Jun;124(2):271-9. doi: 10.1099/00221287-124-2-271.
5
Biology, immunology, and cariogenicity of Streptococcus mutans.
Microbiol Rev. 1980 Jun;44(2):331-84. doi: 10.1128/mr.44.2.331-384.1980.
6
Serological characterization of Streptococcus mutans serotype polysaccharide g and its different molecular weight forms.
Infect Immun. 1984 Aug;45(2):464-9. doi: 10.1128/iai.45.2.464-469.1984.
7
Dental caries: prospects for prevention.
Science. 1971 Sep 24;173(4003):1199-205. doi: 10.1126/science.173.4003.1199.
8
Purification and characterization of Streptococcus mutans group d cell wall polysaccharide antigen.
Infect Immun. 1974 Aug;10(2):361-8. doi: 10.1128/iai.10.2.361-368.1974.
9
Extraction, purification, and chemical and immunological properties of the Streptococcus mutans group "a" polysaccharide cell wall antigen.
Infect Immun. 1973 Aug;8(2):190-8. doi: 10.1128/iai.8.2.190-198.1973.
10
Antigens of Streptococcus mutans. I. Characterization of a serotype-specific determinant from Streptococcus mutans.
Infect Immun. 1973 May;7(5):795-804. doi: 10.1128/iai.7.5.795-804.1973.
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