He Feng J, MacGregor Graham A
Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK,
Pflugers Arch. 2015 Mar;467(3):577-86. doi: 10.1007/s00424-014-1677-x. Epub 2014 Dec 30.
Both dietary salt and sugar are related to blood pressure (BP). The evidence for salt is much stronger, and various types of studies have consistently shown that salt is a major cause of raised BP, and a reduction from the current intake of ≈ 9-12 g/day in most countries of the world to the recommended level of 5-6 g/day lowers BP in both hypertensive and normotensive individuals, in men and women, in all age groups and in all ethnic groups. Countries such as Finland and the UK that have successfully reduced salt intake have demonstrated a reduction in population BP and cardiovascular mortality, with major cost savings to the health service. The mechanisms whereby salt raises BP are not fully understood. The traditional concepts focus on the tendency for an increase in extracellular fluid volume. Increasing evidence suggests that small increases in plasma sodium may play an important role. There are several other factors that also increase BP, one of which is added sugars. The current high intake of added sugars increases obesity which, in turn, raises BP. Recent studies also suggest that added sugars, particularly those in soft drinks, may have a direct effect on BP. However, the relationship between soft drink consumption and BP could be, at least partially, mediated by the effect of salt intake on increasing soft drink consumption. Actions to reduce salt and sugar intake across the whole population will have major beneficial effects on health along with major cost savings.
膳食中的盐和糖都与血压(BP)有关。关于盐的证据更为确凿,各类研究一致表明,盐是血压升高的主要原因,将全球大多数国家目前约9 - 12克/天的摄入量降至推荐的5 - 6克/天,可使高血压患者和血压正常者、男性和女性、所有年龄组以及所有种族的血压降低。芬兰和英国等国成功减少了盐的摄入量,已证明人群血压和心血管疾病死亡率有所降低,同时为医疗服务节省了大量成本。盐升高血压的机制尚未完全明确。传统观念侧重于细胞外液量增加的趋势。越来越多的证据表明,血浆钠的小幅增加可能起重要作用。还有其他几个因素也会升高血压,其中之一是添加糖。目前添加糖的高摄入量会增加肥胖,进而升高血压。近期研究还表明,添加糖,尤其是软饮料中的添加糖,可能对血压有直接影响。然而,软饮料消费与血压之间的关系至少部分可能由盐摄入量对增加软饮料消费的影响所介导。在全体人群中采取减少盐和糖摄入量的措施将对健康产生重大有益影响,同时大幅节省成本。