Department of Diagnostic Radiology, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark.
Metropolitan University College, Radiography Education, Sigurdsgade 26, Copenhagen 2200, Denmark.
Diagnostics (Basel). 2013 Apr 3;3(2):261-70. doi: 10.3390/diagnostics3020261.
Computed Tomography (CT) Perfusion is an evolving method to visualize perfusion in organs and tissue. With the introduction of multidetector CT scanners, it is now possible to cover up to 16 cm in one rotation, and thereby making it possible to scan entire organs such as the liver with a fixed table position. Advances in reconstruction algorithms make it possible to reduce the radiation dose for each examination to acceptable levels. Regarding abdominal imaging, CT perfusion is still considered a research tool, but several studies have proven it as a reliable non-invasive technique for assessment of vascularity. CT perfusion has also been used for tumor characterization, staging of disease, response evaluation of newer drugs targeted towards angiogenesis and as a method for early detection of recurrence after radiation and embolization. There are several software solutions available on the market today based on different perfusion algorithms. However, there is no consensus on which protocol and algorithm to use for specific organs. In this article, the authors give an introduction to CT perfusion in abdominal imaging introducing technical aspects for calculation of perfusion parameters, and considerations on patient preparation. This article also contains clinical cases to illustrate the use of CT perfusion in abdominal imaging.
计算机断层扫描（CT）灌注是一种用于可视化器官和组织灌注的新兴方法。随着多排 CT 扫描仪的引入，现在可以在一次旋转中覆盖多达 16 厘米的范围，从而可以使用固定的台位扫描整个器官，如肝脏。重建算法的进步使得每个检查的辐射剂量都可以降低到可接受的水平。在腹部成像方面，CT 灌注仍然被认为是一种研究工具，但已有多项研究证明其是一种可靠的、非侵入性的血管评估技术。CT 灌注也已用于肿瘤特征描述、疾病分期、针对血管生成的新型药物的反应评估以及作为放射和栓塞后早期复发检测的方法。目前市场上有几种基于不同灌注算法的软件解决方案。然而，对于特定器官，使用哪种方案和算法还没有共识。本文的作者在腹部成像中介绍了 CT 灌注，介绍了计算灌注参数的技术方面，以及对患者准备的考虑。本文还包含了临床病例，以说明 CT 灌注在腹部成像中的应用。
