Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
Adv Mater. 2017 Apr;29(14). doi: 10.1002/adma.201605903. Epub 2017 Feb 23.
Biomineralization is an important tactic by which biological organisms produce hierarchically structured minerals with marvellous functions. Biomineralization studies typically focus on the mediation function of organic matrices on inorganic minerals, which helps scientists to design and synthesize bioinspired functional materials. However, the presence of inorganic minerals may also alter the native behaviours of organic matrices and even biological organisms. This progress report discusses the latest achievements relating to biomineralization mechanisms, the manufacturing of biomimetic materials and relevant applications in biological and biomedical fields. In particular, biomineralized vaccines and algae with improved thermostability and photosynthesis, respectively, demonstrate that biomineralization is a strategy for organism evolution via the rational design of organism-material complexes. The successful modification of biological systems using materials is based on the regulatory effect of inorganic materials on organic organisms, which is another aspect of biomineralization control. Unlike previous studies, this study integrates materials and biological science to achieve a more comprehensive view of the mechanisms and applications of biomineralization.
生物矿化是生物产生具有奇妙功能的分级结构矿物的重要策略。生物矿化研究通常集中在有机基质对无机矿物的介导作用上，这有助于科学家设计和合成仿生功能材料。然而，无机矿物的存在也可能改变有机基质甚至生物的固有行为。本进展报告讨论了与生物矿化机制、仿生材料制造以及生物和生物医学领域相关应用相关的最新成果。特别是，生物矿化疫苗和热稳定性提高的藻类以及光合作用分别表明，生物矿化是通过合理设计生物体-材料复合物进行生物体进化的策略。通过材料成功地修饰生物系统是基于无机材料对有机生物体的调节作用，这是生物矿化控制的另一个方面。与以前的研究不同，本研究整合了材料和生物科学，以更全面地了解生物矿化的机制和应用。
